不育男性精液中的催乳素。

Prolactin in seminal plasma of infertile men.

作者信息

Segal S, Ron M, Laufer N, Ben-David M

出版信息

Arch Androl. 1978;1(1):49-52. doi: 10.3109/01485017808988317.

Abstract

Twenty-one fertile and 103 infertile patients with oligospermia, azoospermia, impaired sperm motility and hypogonadism were evaluated for prolactin concentrations in serum, seminal plasma and split seminal plasma of two fractions. Prolactin concentration in the seminal plasma was two to three times higher than serum prolactin levels in fertile and infertile men. Prolactin concentration of the fraction 2 of the split ejaculate was higher than that of the fraction 1 and of the serum. Excessive high levels of serum prolactin and/or seminal plasma were found only among infertile patients with oligo- and azoospermia, impaired motility and hypogonadotropic hypogonadism. Prolactin is selectively accumulated in fraction 2 of the split ejaculate and affects the constituents of the seminal vesicular fluid, and excessive high prolactin concentrations of either seminal plasma or serum may be associated with male infertility.

摘要

对21名有生育能力的男性以及103名患有少精子症、无精子症、精子活力受损和性腺功能减退的不育男性，检测了血清、精浆以及分为两部分的精浆中催乳素的浓度。在有生育能力和不育男性中，精浆中催乳素浓度比血清催乳素水平高两到三倍。分段射精的第2部分催乳素浓度高于第1部分和血清中的浓度。仅在患有少精子症和无精子症、精子活力受损以及低促性腺激素性腺功能减退的不育患者中发现血清催乳素和/或精浆水平过高。催乳素选择性地积聚在分段射精的第2部分中，并影响精囊液的成分，精浆或血清中过高的催乳素浓度可能与男性不育有关。