脂多糖反应性的新表型标志物。
New phenotypic marker for lipopolysaccharide responsiveness.
作者信息
Gollapudi S V, Gregory S H, Kern M
出版信息
Infect Immun. 1980 Sep;29(3):1202-4. doi: 10.1128/iai.29.3.1202-1204.1980.
Abstract
Lipopolysaccharide-enhanced secretion of non-immunoglobulin proteins by bone marrow cells derived from responder, nonresponder, and low-responder mouse strains did not precisely correlate with the lipopolysaccharide responsiveness assessment based on the mitogenic reactivity of splenocytes. These findings suggest that enhancement of secretion of non-immunoglobulin protein may be useful for further characterization of lipopolysaccharide responsiveness.
摘要
脂多糖增强了来自反应者、无反应者和低反应者小鼠品系的骨髓细胞分泌非免疫球蛋白蛋白质的能力，但这与基于脾细胞有丝分裂反应性的脂多糖反应性评估并不完全相关。这些发现表明，非免疫球蛋白蛋白质分泌的增强可能有助于进一步表征脂多糖反应性。
相似文献
1
New phenotypic marker for lipopolysaccharide responsiveness.脂多糖反应性的新表型标志物。
Infect Immun. 1980 Sep;29(3):1202-4. doi: 10.1128/iai.29.3.1202-1204.1980.
2
A novel mitogen released by lipid A-stimulated bone marrow cells.
J Immunol. 1982 May;128(5):2206-8.
3
Corticosteroids and the humoral immune response of mice. II. Enhancement of bone marrow antibody formation to lipopolysaccharide by high doses of corticosteroids.皮质类固醇与小鼠的体液免疫反应。II. 高剂量皮质类固醇增强骨髓对脂多糖的抗体形成。
Cell Immunol. 1979 Dec;48(2):267-75. doi: 10.1016/0008-8749(79)90121-7.
4
Trypsin does not reconstitute responsiveness to lipopolysaccharide in the strain C3H/HeJ, but is a B-cell mitogen-like lipopolysaccharide, stimulating a different subpopulation.胰蛋白酶不能恢复C3H/HeJ品系对脂多糖的反应性，但它是一种类似B细胞促有丝分裂原的脂多糖，能刺激不同的亚群。
Scand J Immunol. 1989 Feb;29(2):143-9. doi: 10.1111/j.1365-3083.1989.tb01110.x.
5
Functional nuclei of LPS-nonresponder C3H/HeJ mice after transfer into LPS-responder C3H/HeN cells by cell fusion.通过细胞融合将脂多糖无反应性C3H/HeJ小鼠的功能性细胞核转移到脂多糖反应性C3H/HeN细胞后。
Nature. 1981 Mar 5;290(5801):58-9. doi: 10.1038/290058a0.
6
Genetic analysis of the low responsiveness to dextran B512 in CBA/N and C57BL/10ScCr mice.CBA/N和C57BL/10ScCr小鼠对右旋糖酐B512低反应性的遗传分析。
Scand J Immunol. 1983 Sep;18(3):265-7. doi: 10.1111/j.1365-3083.1983.tb00867.x.
7
A search for strain differences in response of mice to mutagenesis by thio-TEPA.对硫代磷酸三乙酯诱变小鼠反应中的品系差异进行研究。
Mutat Res. 1991 Aug;249(2):317-21. doi: 10.1016/0027-5107(91)90006-a.
8
Suppression of phytohemagglutinin and lipopolysaccharide responses in mouse spleen cells by Bacillus Calmette-Guerin.卡介苗对小鼠脾细胞中植物血凝素和脂多糖反应的抑制作用
J Reticuloendothel Soc. 1979 Oct;26(4):349-56.
9
Genetic control of peripheral leukocyte response to endotoxin in mice.小鼠外周血白细胞对内毒素反应的遗传控制
J Immunol. 1980 May;124(5):2468-73.
10
Assignment of a gene that determines erythrocytic guanosine-5'-triphosphate concentration (Gtpc) to mouse chromosome 9.将决定红细胞鸟苷-5'-三磷酸浓度（Gtpc）的基因定位到小鼠9号染色体上。
Genome. 1994 Jun;37(3):399-404. doi: 10.1139/g94-056.
本文引用的文献
1
THE SYNTHESIS AND SECRETION OF gamma-GLOBULINS BY LYMPH NODE CELLS, I. THE MICROSOMAL COMPARTMENTALIZATION OF gamma-GLOBULINS.淋巴结细胞合成与分泌γ-球蛋白，I.γ-球蛋白的微粒体区室化
Proc Natl Acad Sci U S A. 1967 Feb;57(2):417-22. doi: 10.1073/pnas.57.2.417.
2
Lipid A induces cells, uniquely present in bone marrow, to secrete proteins other than immunoglobulins.脂多糖A诱导骨髓中特有的细胞分泌免疫球蛋白以外的蛋白质。
Eur J Biochem. 1980;108(1):233-7. doi: 10.1111/j.1432-1033.1980.tb04716.x.
3
Differentiation of lymphoid cells: the in vitro emergence of immunoglobulin M-secreting cells.
J Immunol. 1973 Sep;111(3):761-9.
4
5
Selective induction of DNA synthesis in T and B lymphocytes.T 淋巴细胞和 B 淋巴细胞中 DNA 合成的选择性诱导。
Cell Immunol. 1972 Aug;4(4):381-93. doi: 10.1016/0008-8749(72)90040-8.
6
7
Genetic control of the antibody response to type 3 pneumococcal polysaccharide in mice. I. Evidence that an X-linked gene plays a decisive role in determining responsiveness.小鼠对3型肺炎球菌多糖抗体反应的遗传控制。I. 有证据表明一个X连锁基因在决定反应性方面起决定性作用。
J Exp Med. 1972 Oct 1;136(4):931-49. doi: 10.1084/jem.136.4.931.
8
The effect of bacterial products on synovial fibroblast function: hypermetabolic changes induced by endotoxin.细菌产物对滑膜成纤维细胞功能的影响：内毒素诱导的代谢亢进变化。
J Clin Invest. 1972 May;51(5):1186-94. doi: 10.1172/JCI106912.
9
Mediation of an endotoxic effect by macrophages.巨噬细胞对内毒素作用的介导。
J Reticuloendothel Soc. 1976 Mar;19(3):187-97.
10
X-linked B-lymphocyte immune defect in CBA/N mice. II. Studies of the mechanisms underlying the immune defect.CBA/N小鼠的X连锁B淋巴细胞免疫缺陷。II.免疫缺陷潜在机制的研究。
J Exp Med. 1975 Sep 1;142(3):637-50. doi: 10.1084/jem.142.3.637.
Zotero 插件