探索全身微波热疗对抗肿瘤免疫的影响。
The search for an influence of whole-body microwave hyperthermia on anti-tumor immunity.
作者信息
Roszkowski W, Wrembel J K, Roszkowski K, Janiak M, Szmigielski S
出版信息
J Cancer Res Clin Oncol. 1980;96(3):311-7. doi: 10.1007/BF00408104.
Abstract
The effect of microwave whole-body hyperthermia was examined on the takes of tumor after i.v. administration of the tumor single cell suspension. It was shown that the longer the exposure to hyperthermia treatment the higher the number of lung nodules obtained by injection of the same dose of tumor cells. Also, the expression of contact hypersenstivity to oxazolone was strongly inhibited after hyperthermia treatment. It was documented that it is possible to transfer the diminished resistance to tumor with bone marrow, whereas impaired responsiveness to oxazolone was transferred with spleen cells or thymocytes.
摘要
在静脉注射肿瘤单细胞悬液后，研究了微波全身热疗对肿瘤接种的影响。结果表明，热疗治疗的暴露时间越长，注射相同剂量肿瘤细胞后获得的肺结节数量就越高。此外，热疗治疗后对恶唑酮的接触性超敏反应表达受到强烈抑制。据记载，骨髓可传递降低的肿瘤抵抗力，而对恶唑酮的反应性受损则可通过脾细胞或胸腺细胞传递。
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引用本文的文献
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A lung-colony assay to determine the radiosensitivity of cells of a solid tumour.一种用于确定实体瘤细胞放射敏感性的肺集落测定法。
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