Jones D M, Eldridge J, Dale B
J Clin Pathol. 1980 Aug;33(8):767-9. doi: 10.1136/jcp.33.8.767.
The antibody response to Campylobacter jejuni/coli infection was investigated in 59 patients involved in two outbreaks of milk-borne infection and in sporadic infections in the community. Agglutinins and complement-fixing (CF) antibodies were detected in nearly all these patients. Agglutinins were present in 25% of normal sera at low titres (not greater than 1/160) but CF antibody titres of 1/4 or 1/8 were present in only 2.0%. The agglutination reactions in convalescent sera were best developed with the homologous or an antigenically similar strain whereas the CF test, with sonicated organisms as antigen, was less strain-specific and was more suitable as a routine test. Antibody was present seven to 10 days after the onset of symptoms.
对59名涉及两次牛奶传播感染暴发及社区散发性感染的患者,研究了其对空肠弯曲菌/结肠弯曲菌感染的抗体反应。几乎所有这些患者均检测到凝集素和补体结合(CF)抗体。25%的正常血清中存在低滴度(不高于1/160)的凝集素,但CF抗体滴度为1/4或1/8的情况仅占2.0%。恢复期血清中的凝集反应在与同源或抗原性相似菌株反应时最为明显,而以超声处理的菌体作为抗原的CF试验,菌株特异性较低,更适合作为常规检测。症状出现后7至10天可检测到抗体。