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胃黏膜上的类弯曲杆菌:培养、组织学及血清学研究

Campylobacter like organisms on the gastric mucosa: culture, histological, and serological studies.

作者信息

Jones D M, Lessells A M, Eldridge J

出版信息

J Clin Pathol. 1984 Sep;37(9):1002-6. doi: 10.1136/jcp.37.9.1002.

DOI:10.1136/jcp.37.9.1002
PMID:6470176
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC498915/
Abstract

Biopsy samples were taken from the gastric mucosa of 50 patients attending a gastroscopy clinic; blood was also taken for serological studies. A campylobacter like organism was grown from 31 patients (62%) and the organism was seen in sections from 27 biopsies. Antibody was found in 31 patients by complement fixation and in 27 by bacterial agglutination. There were strong positive correlations between the presence of the organism, detectable antibody, and histological gastritis. Antibody to the campylobacter like organism was comparatively uncommon in patients without gastritis and in samples from blood donors and antenatal patients.

摘要

从一家胃镜检查诊所的50名患者的胃黏膜中采集活检样本;同时采集血液用于血清学研究。从31名患者(62%)中培养出一种弯曲菌样生物体,并且在27份活检切片中发现了该生物体。通过补体结合试验在31名患者中检测到抗体,通过细菌凝集试验在27名患者中检测到抗体。该生物体的存在、可检测到的抗体与组织学胃炎之间存在强正相关。在没有胃炎的患者以及献血者和产前患者的样本中,针对弯曲菌样生物体的抗体相对不常见。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2183/498915/9288f427aee0/jclinpath00180-0044-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2183/498915/19d079f501d6/jclinpath00180-0043-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2183/498915/450eb2c0d906/jclinpath00180-0043-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2183/498915/9288f427aee0/jclinpath00180-0044-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2183/498915/19d079f501d6/jclinpath00180-0043-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2183/498915/450eb2c0d906/jclinpath00180-0043-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2183/498915/9288f427aee0/jclinpath00180-0044-a.jpg

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本文引用的文献

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Serological response to Campylobacter jejuni/coli infection.对空肠弯曲菌/结肠弯曲菌感染的血清学反应。
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Spiral organisms in endoscopic biopsies of the human stomach.人胃内镜活检中的螺旋状生物体。
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Eradicating Helicobacter pylori reduces hypergastrinaemia during long-term omeprazole treatment.根除幽门螺杆菌可降低长期使用奥美拉唑治疗期间的高胃泌素血症。
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Helicobacter pylori.幽门螺杆菌
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