Skirrow M B
Br Med J. 1977 Jul 2;2(6078):9-11. doi: 10.1136/bmj.2.6078.9.
By selective culture campylobacters (C jejuni and C coli) were isolated from the faeces of 57 (7-1%) out of 803 unselected patients with diarrhoea; none were isolated from 194 people who had not got diarrhoea. Specific agglutinins were found in the sera of 31 out of 38 patients with campylobacter enteritis and 10 of them had a rising titre. Half the patients were aged 15 to 44 years, but the incidence was highest in young children. All the patients with campylobacters had a distinctive clinical illness with severe abdominal pain. Campylobacters are a relatively unrecognised cause of acute enteritis, but these findings suggest that they may be a common cause. Spread of infection was observed within 12 out of 29 households, and in these cases children were usually implicated. Several patients were apparently infected from chickens, both live and dressed, and poultry may be the primary source of the organism. In two cases dogs with diarrhoea were found to be infected with strains indistinguishable from their human contacts. Ten patients acquired their infections while travelling abroad.
通过选择性培养,从803例未经挑选的腹泻患者的粪便中分离出57例(7.1%)弯曲杆菌(空肠弯曲杆菌和结肠弯曲杆菌);在194名未患腹泻的人中未分离出弯曲杆菌。38例弯曲杆菌肠炎患者的血清中发现了特异性凝集素,其中10例凝集素效价呈上升趋势。半数患者年龄在15至44岁之间,但幼儿中的发病率最高。所有弯曲杆菌感染患者都患有独特的临床疾病,伴有严重腹痛。弯曲杆菌是急性肠炎相对未被认识的病因,但这些发现表明它们可能是常见病因。在29户家庭中的12户观察到了感染传播,在这些病例中通常涉及儿童。几名患者显然是通过活鸡和处理好的鸡感染的,家禽可能是该病原体的主要来源。在两例腹泻狗中发现感染了与人类接触者无法区分的菌株。10名患者在国外旅行时感染。