用一株人源空肠弯曲菌对恒河猴进行实验性感染。
Experimental infection of Rhesus monkeys with a human strain of Campylobacter jejuni.
作者信息
Fitzgeorge R B, Baskerville A, Lander K P
出版信息
J Hyg (Lond). 1981 Jun;86(3):343-51. doi: 10.1017/s0022172400069096.
Abstract
Young Rhesus monkeys (Macaca mulatta) were infected orally with a human strain of Campylobacter jejuni. The disease induced was mild, with inappetence and diarrhoea of short duration, but prolonged intermittent excretion of the bacteria in the faeces occurred. Bacteraemia was generally present for 2--3 days and later the organisms localized in the liver and gall bladder. Recovered animals, when challenged with the same strain, showed no clinical symptoms, no bacteraemia, and excreted the organisms in the faeces for only 3 days.
摘要
幼年恒河猴（猕猴）经口感染一株人源空肠弯曲菌。所诱发的疾病症状较轻，表现为食欲不振和短时间腹泻，但粪便中细菌会长期间歇性排出。菌血症一般持续2至3天，之后病菌定位于肝脏和胆囊。康复后的动物再次受到同一菌株攻击时，未出现临床症状，无菌血症，粪便中排出病菌的时间仅为3天。
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