Boesby S, Madsen T, Wallin L
Scand J Gastroenterol. 1980;15(3):325-8. doi: 10.3109/00365528009181478.
The aim of the present study was to investigate whether any differences could be demonstrated between patients with reflux symptoms and an acid-sensitive oesophagus (group I) (positive acid perfusion test) and a matched control group of patients with reflux symptoms and an acid-insensitive oesophagus (group II) (negative acid perfusion test) with respect to other oesophageal function tests (manometry, acid clearing and acid reflux (12-h continuous pH recording)). The two groups consisted of 47 and 46 patients, respectively. No differences were demonstrated between the two groups with respect to gastro-oesophageal sphincter pressure, acid-clearing ability, and acid reflux (irrespective of the criterion used for reflux). From the study it may be concluded that not only hydrochloric acid but other components of the reflux material may be responsible for producing symptoms of gastro-oesophageal reflux.
本研究的目的是调查在其他食管功能测试（测压、酸清除和酸反流（12小时连续pH记录））方面，有反流症状且食管对酸敏感的患者（第一组）（酸灌注试验阳性）与匹配的有反流症状且食管对酸不敏感的患者对照组（第二组）（酸灌注试验阴性）之间是否能显示出任何差异。两组分别由47例和46例患者组成。两组在胃食管括约肌压力、酸清除能力和酸反流方面（无论用于定义反流的标准如何）均未显示出差异。从该研究中可以得出结论，不仅盐酸，反流物质的其他成分也可能导致胃食管反流症状。
