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[利用放射性铬的定量补体结合微量法检测由逆转录病毒D诱导产生的新抗原]

[Detection of new antigens, induced by retrovirus D, by a quantitative complement fixation micromethod using radioactive chromium].

作者信息

Pavliuchenkova R P, Kosiakova N P

出版信息

Vopr Virusol. 1980 Sep-Oct(5):580-3.

PMID:7434739
Abstract

The additional evidence of the existence of antigenic differences between the early virus-induced antigen and structural retrovirus D antigens as well as antigens from human fetus normal tissues was obtained by quantitative complement fixation micromethod using radioactive chromium (51Cr-CFT). In examinations of 13 specimens of cancer tumours and fibroadenomas of the female mammary glands the new antigen was found in 8 cases, including 4 cancer tumours where this antigen could not be detected by the conventional CFT.

摘要

利用放射性铬(51Cr-CFT)定量补体结合微量法,获得了早期病毒诱导抗原与逆转录病毒D结构抗原以及人胎儿正常组织抗原之间存在抗原差异的额外证据。在对13例女性乳腺肿瘤和纤维腺瘤标本的检测中,8例发现了新抗原,其中4例癌性肿瘤用传统补体结合试验未能检测到该抗原。

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