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[烟酰肼给药对大鼠回避反应的影响]

[Effect of nialamide administration on avoidance reactions in rats].

作者信息

Saul'skaia N B

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1980 May-Jun;30(3):530-3.

PMID:7434927
Abstract

Enhanced level of dopamine in the brain caused by one-time administration of nialamide (125 mg/kg into the stomach) does not change the spontaneous motor activity, but increases the number of errors during elaboration of avoidance reaction and during its reversal (changing the side of reinforcement). The rise of the noradrenaline level in the brain, observed after 2 and 3 nialamide administrations does not change parameters of conditioning, but leads to an increase in spontaneous motor activity.

摘要

一次性经胃给予尼亚酰胺(125毫克/千克)导致大脑中多巴胺水平升高,这不会改变自发运动活动,但会增加回避反应形成过程及其反转(改变强化侧)过程中的错误数量。在给予2次和3次尼亚酰胺后观察到大脑中去甲肾上腺素水平升高,这不会改变条件反射参数,但会导致自发运动活动增加。

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1
[Effect of nialamide administration on avoidance reactions in rats].[烟酰肼给药对大鼠回避反应的影响]
Zh Vyssh Nerv Deiat Im I P Pavlova. 1980 May-Jun;30(3):530-3.
2
[Correlation between rate of avoidance reaction elaboration and catecholamine levels in rat brain].
Zh Vyssh Nerv Deiat Im I P Pavlova. 1979 Jul-Aug;29(4):731-6.
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The effects of neuroleptics and nialamide on defensive conditoned reflex in rats.抗精神病药物和烟肼酰胺对大鼠防御性条件反射的影响。
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Comparison of central effects of noradrenaline and dopamine injected into the lateral brain ventricle in rats.大鼠侧脑室注射去甲肾上腺素和多巴胺的中枢效应比较。
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[Various neurochemical mechanisms for the production of conditioned reflexes of various biologicals modalities at the level of the caudate nucleus].[尾状核水平上各种生物学模态条件反射产生的多种神经化学机制]
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[Dopamine concentration in the nigro-striatal system during elaboration and performance of conditioned avoidance reactions of various complexity in rats].[大鼠在形成和执行不同复杂程度的条件性回避反应过程中黑质-纹状体系统中的多巴胺浓度]
Fiziol Zh SSSR Im I M Sechenova. 1981 Jun;67(6):797-803.