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Studies on the regulation of leucine catabolism. Mechanism responsible for oxidizable substrate inhibition and dichloroacetate stimulation of leucine oxidation by the heart.

作者信息

Sans R M, Jolly W W, Harris R A

出版信息

Arch Biochem Biophys. 1980 Apr 1;200(2):336-45. doi: 10.1016/0003-9861(80)90363-x.

DOI:10.1016/0003-9861(80)90363-x
PMID:7436408
Abstract
摘要

相似文献

1
Studies on the regulation of leucine catabolism. Mechanism responsible for oxidizable substrate inhibition and dichloroacetate stimulation of leucine oxidation by the heart.亮氨酸分解代谢调节的研究。心脏中可氧化底物抑制和二氯乙酸刺激亮氨酸氧化的机制。
Arch Biochem Biophys. 1980 Apr 1;200(2):336-45. doi: 10.1016/0003-9861(80)90363-x.
2
Differential effect of dichloroacetate on branched-chain amino acid catabolism in perfused rat hindlimbs.二氯乙酸对灌注大鼠后肢支链氨基酸分解代谢的差异作用。
FEBS Lett. 1985 Apr 8;183(1):33-6. doi: 10.1016/0014-5793(85)80948-0.
3
Branched-chain amino acid metabolism.支链氨基酸代谢
Annu Rev Nutr. 1984;4:409-54. doi: 10.1146/annurev.nu.04.070184.002205.
4
Degradation of branched-chain amino acids and their derived 2-oxo acids and fatty acids in human and rat heart and skeletal muscle.人和大鼠心脏及骨骼肌中支链氨基酸及其衍生的2-氧代酸和脂肪酸的降解
Biochem Med. 1982 Aug;28(1):16-31. doi: 10.1016/0006-2944(82)90051-5.
5
Studies on the activation and inactivation of the branched chain alpha-keto acid dehydrogenase in the perfused rat heart.灌注大鼠心脏中支链α-酮酸脱氢酶激活与失活的研究。
J Biol Chem. 1980 Oct 25;255(20):9773-81.
6
Active and inactive forms of branched-chain 2-oxoacid dehydrogenase complex in rat heart and skeletal muscle.大鼠心脏和骨骼肌中支链2-氧代酸脱氢酶复合物的活性和非活性形式
FEBS Lett. 1980 Apr 7;112(2):186-90. doi: 10.1016/0014-5793(80)80176-1.
7
Regulation of branched-chain amino acid metabolism.
Biochem Soc Trans. 1986 Dec;14(6):1005-8. doi: 10.1042/bst0141005.
8
Catabolism of branched-chain amino acids by diaphragm muscles of fasted and diabetic rats.禁食和糖尿病大鼠膈肌对支链氨基酸的分解代谢
Metabolism. 1985 Aug;34(8):702-11. doi: 10.1016/0026-0495(85)90018-6.
9
Effect of carnitine and branched-chain acylcarnitines on the 2-oxo acid dehydrogenase activity in intact mitochondria of rat muscle.肉碱和支链酰基肉碱对大鼠肌肉完整线粒体中2-氧代酸脱氢酶活性的影响。
Int J Biochem. 1980;12(4):559-65. doi: 10.1016/0020-711x(80)90007-5.
10
Studies on the regulation of the branched chain alpha-keto acid dehydrogenase in the perfused rat heart.灌注大鼠心脏中支链α-酮酸脱氢酶调节的研究
J Biol Chem. 1979 Oct 25;254(20):10453-8.

引用本文的文献

1
Effects of leucine supplementation and serum withdrawal on branched-chain amino acid pathway gene and protein expression in mouse adipocytes.亮氨酸补充和血清去除对小鼠脂肪细胞中支链氨基酸途径基因和蛋白质表达的影响。
PLoS One. 2014 Jul 22;9(7):e102615. doi: 10.1371/journal.pone.0102615. eCollection 2014.
2
The regulation of branched-chain 2-oxo acid dehydrogenase of liver, kidney and heart by phosphorylation.肝脏、肾脏和心脏中支链2-氧代酸脱氢酶的磷酸化调节。
Biochem J. 1981 May 15;196(2):459-69. doi: 10.1042/bj1960459.
3
Increase of the activity state and loss of total activity of the branched-chain 2-oxo acid dehydrogenase in rat diaphragm during incubation.
孵育过程中大鼠膈肌支链2-氧代酸脱氢酶活性状态增加及总活性丧失。
Biochem J. 1984 Dec 1;224(2):491-6. doi: 10.1042/bj2240491.
4
Branched-chain amino acid metabolism and alanine formation in rat diaphragm muscle in vitro. Effects of dichloroacetate.大鼠膈肌体外支链氨基酸代谢及丙氨酸生成。二氯乙酸的作用。
Biochem J. 1984 Nov 1;223(3):831-5. doi: 10.1042/bj2230831.
5
Regulatory effects of fatty acids on decarboxylation of leucine and 4-methyl-2-oxopentanoate in the perfused rat heart.脂肪酸对灌注大鼠心脏中亮氨酸和4-甲基-2-氧代戊酸脱羧作用的调节效应
Biochem J. 1984 Aug 1;221(3):593-9. doi: 10.1042/bj2210593.
6
Amino acid oxidation and alanine production in rat hemidiaphragm in vitro. Effects of dichloroacetate.大鼠半膈膜体外氨基酸氧化及丙氨酸生成。二氯乙酸的作用。
Biochem J. 1984 Oct 1;223(1):113-7. doi: 10.1042/bj2230113.
7
Role of activation of myocardial branched-chain 2-oxo acid dehydrogenase complex in the regulation of leucine decarboxylation during cardiac work in vitro.心肌支链2-氧代酸脱氢酶复合体激活在体外心脏工作期间亮氨酸脱羧调节中的作用
Biochem J. 1987 Dec 1;248(2):423-8. doi: 10.1042/bj2480423.
8
Acute regulation of the branched-chain 2-oxo acid dehydrogenase complex by adrenaline and glucagon in the perfused rat heart.肾上腺素和胰高血糖素对灌注大鼠心脏中支链2-氧代酸脱氢酶复合体的急性调节作用
Biochem J. 1988 Mar 15;250(3):835-41. doi: 10.1042/bj2500835.
9
Regulation of the branched-chain 2-oxo acid dehydrogenase complex in hepatocytes isolated from rats fed on a low-protein diet.低蛋白饮食喂养大鼠分离的肝细胞中支链2-氧代酸脱氢酶复合体的调节
Biochem J. 1986 Mar 1;234(2):285-94. doi: 10.1042/bj2340285.