羟基犬尿氨酸/羟基邻氨基苯甲酸比率与热性惊厥
Hydroxykynurenine/hydroxyanthranilic acid ratios and febrile convulsions.
作者信息
McKiernan J, Mellor D, Court S, Edson J, Lacey K
出版信息
Arch Dis Child. 1980 Nov;55(11):873-5. doi: 10.1136/adc.55.11.873.
Abstract
Hydroxykynurenine/hydroxyanthranilic acid ratios were measured in children with febrile convulsions, afebrile fits, and fever, as well as in healthy controls. Increased ratios were found not only in the children who had fits but also in the children who were febrile and did not have fits. It is suggested that a raised hydroxykynurenine/hydroxyanthranilic acid ratio does not necessarily indicate vitamin B6 deficiency but may represent a nonspecific response of tryptophan metabolism to stress.
摘要
在热性惊厥、无热惊厥和发热儿童以及健康对照中测量了羟基犬尿氨酸/羟基邻氨基苯甲酸的比率。不仅在发生惊厥的儿童中发现比率升高，而且在发热但未发生惊厥的儿童中也发现比率升高。有人提出，升高的羟基犬尿氨酸/羟基邻氨基苯甲酸比率不一定表明维生素B6缺乏，而可能代表色氨酸代谢对应激的非特异性反应。
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本文引用的文献
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Pyridoxine hydrochloride (vitamin B6) need in infants and children; a study in patients with anemia, convulsions, and acute infections.盐酸吡哆醇（维生素B6）在婴幼儿中的需求；对贫血、惊厥和急性感染患者的一项研究
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