Mollah Md Abid Hossain, Dey Probhat Ranjan, Tarafdar S A, Akhter Sohela, Ahmed Shakil, Hassan Tariq, Begum Nargis Ara, Nahar Nazmun
Department of Pediatrics, Dhaka Medical College Hospital, Dhaka, Bangladesh.
Indian J Pediatr. 2002 Oct;69(10):859-61. doi: 10.1007/BF02723706.
This prospective study was carried out from July-December 1999 to see the status of zinc in CSF of children with febrile convulsion and to compare this to that of control.
Forty-two cases of febrile convulsion and 30 controls (fever without convulsion) were enrolled into the study. CSF zinc was estimated by atomic absorption spectrophotometry (AAS) in Atomic Energy Center, Dhaka and compared between the two groups.
The mean zinc level in CSF in the study sample was 40.19mgm/L and that in control was 74.98mgm/L. This difference was statistically significant (p<0.001).
The study concludes that a significantly lower of zinc exists in CSF of children with febrile. However no relationship was found between CSF zinc status with age, sex, degree & duration of fever and time of lumbar puncture after convulsion.
本前瞻性研究于1999年7月至12月进行，旨在观察热性惊厥患儿脑脊液中锌的状况，并与对照组进行比较。
42例热性惊厥患儿和30例对照组（发热无惊厥）纳入本研究。在达卡原子能中心采用原子吸收分光光度法（AAS）测定脑脊液锌含量，并在两组间进行比较。
研究样本中脑脊液锌的平均水平为40.19mgm/L，对照组为74.98mgm/L。这种差异具有统计学意义（p<0.001）。
该研究得出结论，热性惊厥患儿脑脊液中锌含量显著降低。然而，未发现脑脊液锌状况与年龄、性别、发热程度和持续时间以及惊厥后腰椎穿刺时间之间存在关联。
