Moncrieff M, Bamford M, Benson J, Bodden J
Arch Dis Child. 1980 Sep;55(9):723-5. doi: 10.1136/adc.55.9.723.
Urine was cultured from 51 healthy preterm babies. If the initial bag specimen grew more than 50 000 organisms/ml, a second bag specimen was cultured. After two positive bag specimens a suprapubic urine was cultured. Significant bacteriuria was excluded on the basis of one or two bag specimens in 90% of the babies. Suprapubic urine was sterile in a further 11 babies. Four babies with positive bag specimens were unfortunately not completely investigated: 2 had mixed growths and 2 had pure growths of 100 000 organisms/ml. As we and others consider that bacteriuria can only be diagnosed on a suprapubic sample of urine the incidence of proved infection in our series was zero. If both the babies with a pure growth of 100 000 organisms/ml had true bacteriuria, the incidence would rise to 1.3%. In view of the difficulties in obtaining clean urine samples in preterm babies and as the incidence of bacteriuria is so low, we do not recommend that healthy preterm babies be screened for bacteriuria.
对51名健康早产婴儿的尿液进行了培养。如果最初的尿袋标本中细菌数量超过50000个/毫升，则对第二个尿袋标本进行培养。在两份尿袋标本呈阳性后，对耻骨上尿液进行培养。90%的婴儿根据一或两份尿袋标本排除了显著菌尿。另有11名婴儿的耻骨上尿液无菌。不幸的是，4名尿袋标本呈阳性的婴儿未得到彻底检查：2名有混合菌生长，2名有100000个/毫升的纯菌生长。由于我们和其他人认为只有通过耻骨上尿液样本才能诊断菌尿，因此我们系列研究中确诊感染的发生率为零。如果两名有100000个/毫升纯菌生长的婴儿确实患有菌尿，那么发生率将升至1.3%。鉴于在早产婴儿中获取清洁尿液样本存在困难，且菌尿发生率很低，我们不建议对健康早产婴儿进行菌尿筛查。
