Liefman C E
Aust Vet J. 1980 Mar;56(3):119-22. doi: 10.1111/j.1751-0813.1980.tb05647.x.
The protection afforded by active, passive and combined active-passive methods of immunisation against tetanus was examined in previously unimmunised horses. Three groups of horses were injected; one with tetanus toxoid alone, one with tetanus antitoxin alone and one in which the tetanus toxoid and tetanus antitoxin were injected simultaneously. The protection afforded was determined by monitoring the levels of antitoxin achieved in the horses by each of these methods. The results obtained demonstrated the effectiveness of the combined active-passive method in affording rapid and prolonged protection and enabled the examination of some of the factors involved in active and in passive immunisation when used alone. The advantages obtained by the use of the combined active-passive method in protecting unimmunised horses suddenly placed at risk to infection are outlined.
在之前未免疫的马匹中，研究了主动免疫、被动免疫以及主动 - 被动联合免疫方法对破伤风的保护作用。对三组马匹进行了注射：一组仅注射破伤风类毒素，一组仅注射破伤风抗毒素，另一组同时注射破伤风类毒素和破伤风抗毒素。通过监测这些方法在马匹体内产生的抗毒素水平来确定所提供的保护作用。所获得的结果证明了主动 - 被动联合方法在提供快速且持久保护方面的有效性，并且能够单独研究主动免疫和被动免疫中涉及的一些因素。概述了使用主动 - 被动联合方法保护突然面临感染风险的未免疫马匹所获得的优势。
