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肺输入阻抗在右心室功能中的意义。

Significance of pulmonary input impedance in right ventricular performance.

作者信息

Pouleur H, Lefevre J, van Eyll C, Jaumin P M, Charlier A A

出版信息

Cardiovasc Res. 1978 Oct;12(10):617-29. doi: 10.1093/cvr/12.10.617.

DOI:10.1093/cvr/12.10.617
PMID:743696
Abstract

Right ventricular adaptation to changes in pulmonary input impedance was studied in open-chest dogs. When identical increases in pulmonary vascular resistance are imposed by two different manoeuvres (lung inflation and clamping of the left pulmonary artery), external power and pressure-time integral of the right ventricle at similar filling pressure are always greater during clamping than during inflation. Further studies demonstrate that, at equal increases in pulmonary input impedance modulus at 0 Hz, the clamping produces a greater change in the sum of the first three harmonics of impedance than the inflation (respectively +77% and -10% vs control modulus; -82% and +8% vs control phase). These impedance changes could explain the different behaviour of the right ventricle either by better matching of the ventricular internal impedance or by functional modification of the outflow tract.

摘要

在开胸犬中研究了右心室对肺输入阻抗变化的适应性。当通过两种不同操作(肺充气和左肺动脉夹闭)使肺血管阻力产生相同增加时,在相似的充盈压下,夹闭期间右心室的外部功率和压力 - 时间积分总是大于充气期间。进一步研究表明,在0 Hz时肺输入阻抗模量同等增加的情况下,夹闭比充气在阻抗的前三个谐波总和上产生更大变化(相对于对照模量分别为 +77% 和 -10%;相对于对照相位为 -82% 和 +8%)。这些阻抗变化可以通过心室内部阻抗的更好匹配或流出道的功能改变来解释右心室的不同行为。

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