Gmelin E, Theiss W
Cardiovasc Radiol. 1978 Jul 25;1(3):157-64. doi: 10.1007/BF02552027.
Forty-three patients with deep vein thrombosis were given fibrinolytic therapy with streptokinase and/or urokinase. In all patients the diagnosis was made phlebographically, and repeat phlebography was performed after termination of therapy. Sixty-four of 104 vein segments initially occluded (62%) were partially or completely recanalized. No vein segments particularly suitable for fibrinolytic therapy could be defined. The therapy was as successful in cases in which the thrombosis extended over several segments as in those in which the occlusions involved only one or two segments. Similarly, there was no difference in the success rate for thrombi that were still freely floating and for thrombi that occluded the veins completely. It is recommended that fibrinolytic therapy be given in suitable cases in which clinical symptoms have persisted up to two weeks; in some cases this limit may even be extended up to one month.
43例深静脉血栓形成患者接受了链激酶和/或尿激酶溶栓治疗。所有患者均通过静脉造影进行诊断，并在治疗结束后进行重复静脉造影。最初闭塞的104个静脉段中有64个（62%）部分或完全再通。未发现特别适合溶栓治疗的静脉段。血栓延伸至多个节段的病例与仅累及一两个节段闭塞的病例，溶栓治疗效果相同。同样，仍可自由漂浮的血栓和完全阻塞静脉的血栓，其成功率也无差异。建议在临床症状持续长达两周的合适病例中进行溶栓治疗；在某些情况下，这个时限甚至可延长至一个月。
