Clark S, Zorab P A
Clin Orthop Relat Res. 1978 Nov-Dec(137):217-26.
Centiles for 24 hour urinary total hydroxyproline are useful in monitoring growth and the effect of treatment in children with orthopedic diseases such as scoliosis, where growth is difficult to measure by anthropometric means. The centiles have been calculated from the data of a 5 year longitudinal study on 100 normal adolescent schoolchildren. Hydroxyproline estimations and assessments of growth were done 3 times a year. The rate of growth (height velocity) can be correlated with hydroxyproline levels found in adolescents.
24小时尿总羟脯氨酸百分位数有助于监测患有脊柱侧弯等骨科疾病儿童的生长情况及治疗效果，因为通过人体测量方法很难测量这些儿童的生长情况。这些百分位数是根据对100名正常青春期学童进行的为期5年的纵向研究数据计算得出的。每年进行3次羟脯氨酸测定和生长评估。生长速率（身高增长速度）可以与青少年体内的羟脯氨酸水平相关联。
