氯磺丙脲-乙醇潮红反应对糖尿病患者的个体遗传咨询没有帮助。
Chlorpropamide-alcohol flushing is not useful for individual genetic counseling of diabetic patients.
作者信息
Dreyer M, Kühnau J, Rüdiger H W
出版信息
Clin Genet. 1980 Sep;18(3):189-90. doi: 10.1111/j.1399-0004.1980.tb00869.x.
Abstract
The presence or absence of chlorpropamide-alcohol flushing (CPAF) was not correlated with the classification of diabetes. Five out of twelve patients with juvenile-onset diabetes (JOD) flushed and three out of four patients with maturity-onset diabetes in young people (MODY) did not flush. Consequently, CPAF cannot be used for individual genetic counseling in diabetes mellitus.
摘要
氯磺丙脲-乙醇潮红反应（CPAF）的有无与糖尿病的分类无关。12例青少年发病型糖尿病（JOD）患者中有5例出现潮红反应，而4例青年人成年发病型糖尿病（MODY）患者中有3例未出现潮红反应。因此，CPAF不能用于糖尿病的个体遗传咨询。
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