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关于前中期染色体排列到赤道面的机制:染色体速度与纺锤体上位置的关系

On the mechanism of prometaphase congression: chromosome velocity as a function of position on the spindle.

作者信息

Wise D

出版信息

Chromosoma. 1978 Nov 22;69(2):231-41. doi: 10.1007/BF00329921.

DOI:10.1007/BF00329921
PMID:743900
Abstract

Rates of movement of univalents at prometaphase and of half-bivalents at anaphase in living cricket and grasshopper spermatocytes were determined as a function of the distance from the pole toward which the movement was directed. In the artificially produced univalents of cricket cells, correlation coefficients for rate versus distance form the pole were widely disparate from movement to movement and there was no consistent relationship between velocity and distance from the pole. However, in the naturally occurring univalents of grasshopper cells, there was a significant positive correlation between velocity and distance from the pole. In both cricket and grasshopper cells, there was no consistent correlation between rate of movement and distance from the pole for half-bivalents at anaphase. The prometaphase data from grasshopper cells support the simple hypothesis of Ostergren (1950) that congression results from the application to chromosomes of forces which increase with increasing distance from the pole. Furthermore, these data are consistent with models of force production which suppose that the relationship between force (reflected as velocity) and distance from the pole is a linear one.

摘要

测定了活蟋蟀和蚱蜢精母细胞中前中期单价体以及后期半二价体的移动速率与朝着移动方向的极之间距离的函数关系。在蟋蟀细胞人工产生的单价体中,速率与距极的距离之间的相关系数在不同移动之间差异很大,速度与距极的距离之间没有一致的关系。然而,在蚱蜢细胞自然存在的单价体中,速度与距极的距离之间存在显著的正相关。在蟋蟀和蚱蜢细胞中,后期半二价体的移动速率与距极的距离之间均没有一致的相关性。蚱蜢细胞的前中期数据支持了奥斯特格伦(1950年)的简单假设,即染色体向赤道板移动是由于施加在染色体上的力随着距极距离的增加而增大。此外,这些数据与力产生模型一致,该模型假设力(以速度反映)与距极的距离之间的关系是线性的。

相似文献

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2
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Evolution and the meaning of metaphase.进化与中期的意义。
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引用本文的文献

1
A Brief History of Research on Mitotic Mechanisms.有丝分裂机制研究简史
Biology (Basel). 2016 Dec 21;5(4):55. doi: 10.3390/biology5040055.
2
Relationship between the arrangement of microtubules and chromosome behaviour of syntelic autosomal univalents during prometaphase in crane fly spermatocytes.大蚊精母细胞前中期着丝粒单侧连接常染色体单价体的微管排列与染色体行为之间的关系
Chromosoma. 1986;94(5):412-8. doi: 10.1007/BF00328642.
3
On the mechanism of anaphase A: evidence that ATP is needed for microtubule disassembly and not generation of polewards force.

本文引用的文献

1
Equilibrium of trivalents at metaphase.
Hereditas. 1945;31(3-4):499.
2
Equilibrium of trivalents and the mechanism of chromosome movements.三价体的平衡与染色体运动机制
Hereditas. 1945;31(3-4):498.
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Recurrent pole-to-pole movements of the sex chromosome during prometaphase I in Melanoplus differentialis spermatocytes.在异跗螽精母细胞有丝分裂前期 I 期间,性染色体反复进行极到极的移动。
Chromosoma. 1961;12:97-115. doi: 10.1007/BF00328917.
关于后期A的机制:有证据表明,ATP是微管解聚所必需的,而非产生向极力所必需的。
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Poleward force at the kinetochore in metaphase depends on the number of kinetochore microtubules.中期着丝粒处的向极力取决于着丝粒微管的数量。
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UV microbeam irradiations of the mitotic spindle. II. Spindle fiber dynamics and force production.有丝分裂纺锤体的紫外线微束照射。II. 纺锤体纤维动力学与力的产生
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4
[Spermatocyte division of Tipulae. III. Movement behavior of chromosomes in translocation heterozygotes of Tipula oleracea].[大蚊精母细胞分裂。III. 甘蓝大蚊易位杂合子中染色体的运动行为]
Chromosoma. 1961;12:116-89. doi: 10.1007/BF00328918.
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[Multiple sex chromosomes in Ostracoda cypria, their evolution and division characteristics].[介形虫Cypria中的多条性染色体、其进化及分裂特征]
Chromosoma. 1958;9(5):359-440.
6
Chromosome micromanipulation. II. Induced reorientation and the experimental control of segregation in meiosis.染色体显微操作。II. 减数分裂中诱导的重新定向和分离的实验控制。
Chromosoma. 1967;21(1):17-50. doi: 10.1007/BF00330545.
7
Sex chromosomes and meiotic mechanisms in some African and Australian mantids.
Chromosoma. 1965 May 26;16(5):521-47. doi: 10.1007/BF00326972.
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Mitosis.有丝分裂
Adv Cell Biol. 1971;2:225-97. doi: 10.1007/978-1-4615-9588-5_5.
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Cellular mechanisms of chromosome distribution.染色体分配的细胞机制。
Int Rev Cytol. 1970:Suppl 2:1-173.
10
Chromosome movement: current models and experiments on living cells.染色体运动:活细胞的当前模型与实验
Soc Gen Physiol Ser. 1975;30:97-117.