胃酸刺激胃泌素途径中的胆碱能成分。
Cholinergic components in the gastrin pathway of gastric acid stimulation.
作者信息
Szelenyi I
出版信息
Experientia. 1980 Aug 15;36(8):973-4. doi: 10.1007/BF01953827.
PMID:7439333
Abstract
In the isolated whole stomach of the mouse, cimetidine and atropine appear to be specific antagonists of histamine- and acetylcholine-induced stimulation of parietal cells. Interactions were demonstrated between cimetidine and gastrin, atropine and gastrin, respectively. In addition to a histaminergic pathway of gastrin stimulation, a cholinergic part, probably postganglionic, can be taken into consideration.
摘要
在小鼠分离的整个胃中，西咪替丁和阿托品似乎分别是组胺和乙酰胆碱诱导壁细胞刺激的特异性拮抗剂。分别证实了西咪替丁与胃泌素、阿托品与胃泌素之间的相互作用。除了胃泌素刺激的组胺能途径外，还可考虑一条胆碱能途径，可能是节后的。
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