Hirano T, Niijima A
J Auton Nerv Syst. 1980 Mar;1(3):283-90. doi: 10.1016/0165-1838(80)90023-5.
Efferent nerve activity was recorded from nerve filaments dissected from the adrenal nerves in the rabbit before and after deafferentation of baroreceptors. Suppression of efferent activity of the adrenal nerve was observed following an injection of DL-epinephrine into the carotid artery. This suppression of adrenal nerve activity preceded the hypertension induced by epinephrine. An injection of lidocaine into the carotid artery caused a temporary suspension of the inhibitory effect of epinephrine. Adrenergic blocking agents also inhibited the suppressive effect of epinephrine. An injection of arterial blood collected during electrical stimulation of the splanchnic nerve reduced adrenal nerve activity. The present results suggest that catecholamines released from the adrenal medulla reflexly inhibit adrenal nerve activity through epinephrine-sensitive structure in the brain.
在兔压力感受器去传入神经前后，记录从肾上腺神经分离出的神经纤维的传出神经活动。向颈动脉注射DL-肾上腺素后，观察到肾上腺神经传出活动受到抑制。这种肾上腺神经活动的抑制在肾上腺素诱导的高血压之前出现。向颈动脉注射利多卡因可使肾上腺素的抑制作用暂时停止。肾上腺素能阻断剂也抑制肾上腺素的抑制作用。注射在内脏神经电刺激期间采集的动脉血可降低肾上腺神经活动。目前的结果表明，肾上腺髓质释放的儿茶酚胺通过脑中的肾上腺素敏感结构反射性地抑制肾上腺神经活动。
