前列腺腺癌患者的人类白细胞A和B抗原

Human leukocyte A and B antigens in patients with prostatic adenocarcinoma.

作者信息

Barry J M, Goldstein A, Hubbard M

出版信息

J Urol. 1980 Dec;124(6):847-8. doi: 10.1016/s0022-5347(17)55694-3.

Abstract

An increasing number of diseases has been associated with specific human leukocyte antigens. A total of 100 white men with adenocarcinoma of the prostate was serotyped for 32 A and B antigens. Compared to a control population of 169 white subjects relative risks of 2 or more were associated with the antigens A11 and A29. Relative risks of 0.20 or less were associated with the antigens AW23, BW21 and BW22. None of these relative risks was significant statistically. We were unable to demonstrate a significant human leukocyte A or B antigen association with adenocarcinoma of the prostate.

摘要

越来越多的疾病已与特定的人类白细胞抗原相关联。对100名患有前列腺腺癌的白人男性进行了32种A和B抗原的血清分型。与169名白人对照人群相比，抗原A11和A29的相对风险为2或更高。抗原AW23、BW21和BW22的相对风险为0.20或更低。这些相对风险在统计学上均无显著意义。我们未能证明人类白细胞A或B抗原与前列腺腺癌之间存在显著关联。