Baruffini A, Borgna P, Calderara G
Farmaco Sci. 1978 Aug;33(8):641-50.
Asimmetric N,N-dialkylamides of benzoic acids variously trisubstituted on the nucleus were prepared and tested for phytotoxicity in pre- and post-emergence experiments. These amides are characterized by the presence on the amidic N of a sec.butyl or a 1-methylbutyl or a 1-ethylpropyl group and a second alkyl group of varying weight and nature. For reference the Authors prepared and studied 2,3,5-trichlorobenzamides bearing on the N atom a tert.butyl and a second linear C2 leads to C4 alkyl. The substances studied generally proved very active against the weeds tested and showed marked specificity of action towards Setaria and Echinochloa. The compounds proving most active against the weeds were also tested against plants of agricultural interest. In general these asymmetric amides proved more phytotoxic against agrarian species than the corresponding N,N-di,sec.butylamides studied previously.
制备了在核上有不同三取代的苯甲酸不对称N,N -二烷基酰胺，并在苗前和苗后试验中测试了其植物毒性。这些酰胺的特征在于酰胺基N上存在仲丁基、1 -甲基丁基或1 -乙基丙基以及另一个重量和性质不同的烷基。作为参考，作者制备并研究了在N原子上带有叔丁基和第二个直链C2至C4烷基的2,3,5 -三氯苯甲酰胺。所研究的物质通常对测试的杂草非常有效，并且对狗尾草属和稗属表现出明显的作用特异性。对杂草最有效的化合物也针对具有农业价值的植物进行了测试。一般来说，这些不对称酰胺对农作物的植物毒性比先前研究的相应N,N -二仲丁基酰胺更大。
