Baruffini A, Pagani G, Caccialanza G
Farmaco Sci. 1978 Sep;33(9):705-12.
N,N-di-(1-ethylpropyl)amides of benzoic and naphthoic acids suitable substituted in the nucleus were prepared and tested for selective phytotoxic activity in both pre- and post-emergence tests against some weed species. All the amides tested showed good generic phytotoxicity, often with good selectivity, on absorbance through the roots of graminaceous weeds. The nature and degree of phytotoxic activity was influenced by the nature, position and number of substituents on the aromatic nucleus. Confirmation was again obtained of the importance of alpha-substitution in the two alkyl substituents on the amide nitrogen in producing selective phytotoxic activity.
制备了在核上适当取代的苯甲酸和萘甲酸的N,N-二-(1-乙基丙基)酰胺,并在芽前和芽后试验中针对一些杂草物种测试了其选择性植物毒性活性。所有测试的酰胺对禾本科杂草的根部吸收均表现出良好的一般植物毒性,且通常具有良好的选择性。植物毒性活性的性质和程度受芳核上取代基的性质、位置和数量的影响。再次证实了酰胺氮上两个烷基取代基中的α-取代在产生选择性植物毒性活性方面的重要性。