[Influence of the amount of lipid calories in the diet on the nutritional effects of oxythioquinox in the rat].

The effects of oxythioquinox (200 mg/kg fresh food for 30 days) on the growth, feeding, body composition and weight of various organs were studied in rats receiving isocaloric diets containing varying amounts of alimentary lipid (3, 18, 35 and 49%). With the exception of the liver, the kidneys and the ratio of ingested protein/gain in body proteins, which increased, all the investigated parameters showed a significant decrease under the effect of oxythioquinox. Since the various diets were isocaloric and the ratio total calories/proteins (g) was constant, no effects directly due to the level of lipid were seen on the parameters studied except the weight of the caecum which decreased. The interactions observed mirror an antagonism between the effects of the lipids and those of oxythioquinox.