Spagnoli L G, Viilaschi S, Oddi G, Cocchieri G
Tumori. 1980 Jun 30;66(3):397-404. doi: 10.1177/030089168006600312.
The electron microscopic observation of 2 parathyroid adenomas led to detection, in addition to elements which can also be found in nonneoplastic cells and related to the functional state, of organelles more characteristically associated with neoplastic cells. Indeed, intracytoplasmic cilia and annulate lamellae are commonly regarded as an expression of cellular atypia rather then distinctive of the adenoma cell. Moreover, our study seems to show that annulate lamellae are correlated with the hormonal synthesis more than with the rate of growth of the neoplastic tissue.
对2例甲状旁腺腺瘤进行电子显微镜观察发现，除了在非肿瘤细胞中也能发现且与功能状态相关的成分外，还发现了一些更具肿瘤细胞特征的细胞器。确实，胞质内纤毛和环状片层通常被视为细胞异型性的一种表现，而非腺瘤细胞所特有。此外，我们的研究似乎表明，环状片层与激素合成的相关性大于与肿瘤组织生长速度的相关性。
