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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Huizing G, Beckett A H

Xenobiotica. 1980 Jul-Aug;10(7-8):593-602. doi: 10.3109/00498258009033793.

N-(1'-Benzyl-4'-piperidyl-N-oxide)-4-amino-5-chloro-2-methoxybenzamide, N-(4'-(N-hydroxylpiperidyl)-4-amino-5-chloro-2-methoxybenzamide and N-(4'-(delta 1'-piperidyl-N-oxide))-4-amino-5-chloro-2-methoxybenzamide were obtained from chloroform extracts of incubation mixtures of clebopride or desbenzyl clebopride with 9000 g supernatant of liver homogenates of male NZW rabbits. 2. These metabolites were identified using electron impact (low and high resolution) and field desorption mass spectrometry, and computer averaged time proton magnetic resonance spectroscopy.

N-（1'-苄基-4'-哌啶基-N-氧化物）-4-氨基-5-氯-2-甲氧基苯甲酰胺、N-（4'-（N-羟基哌啶基）-4-氨基-5-氯-2-甲氧基苯甲酰胺和N-（4'-（δ1'-哌啶基-N-氧化物））-4-氨基-5-氯-2-甲氧基苯甲酰胺是从氯氮平或去苄基氯氮平与雄性新西兰白兔肝脏匀浆9000g上清液的孵育混合物的氯仿提取物中获得的。2. 使用电子轰击（低分辨率和高分辨率）、场解吸质谱以及计算机平均时间质子磁共振波谱对这些代谢物进行了鉴定。

Huizing G, Beckett A H

Xenobiotica. 1980 Jul-Aug;10(7-8):593-602. doi: 10.3109/00498258009033793.

N-(1'-Benzyl-4'-piperidyl-N-oxide)-4-amino-5-chloro-2-methoxybenzamide, N-(4'-(N-hydroxylpiperidyl)-4-amino-5-chloro-2-methoxybenzamide and N-(4'-(delta 1'-piperidyl-N-oxide))-4-amino-5-chloro-2-methoxybenzamide were obtained from chloroform extracts of incubation mixtures of clebopride or desbenzyl clebopride with 9000 g supernatant of liver homogenates of male NZW rabbits. 2. These metabolites were identified using electron impact (low and high resolution) and field desorption mass spectrometry, and computer averaged time proton magnetic resonance spectroscopy.

N-（1'-苄基-4'-哌啶基-N-氧化物）-4-氨基-5-氯-2-甲氧基苯甲酰胺、N-（4'-（N-羟基哌啶基）-4-氨基-5-氯-2-甲氧基苯甲酰胺和N-（4'-（δ1'-哌啶基-N-氧化物））-4-氨基-5-氯-2-甲氧基苯甲酰胺是从氯氮平或去苄基氯氮平与雄性新西兰白兔肝脏匀浆9000g上清液的孵育混合物的氯仿提取物中获得的。2. 使用电子轰击（低分辨率和高分辨率）、场解吸质谱以及计算机平均时间质子磁共振波谱对这些代谢物进行了鉴定。