Proppe K H, Scully R E
Am J Clin Pathol. 1980 Nov;74(5):607-19. doi: 10.1093/ajcp/74.5.607.
Ten cases of a distinctive testicular neoplasm characterized by large cells with abundant eosinophilic cytoplasm and calcification are reported together with two similar cases from the literature. A Sertoli cell origin of these tumors was established by their architectural and cytologic characteristics, as well as their frequent growth within seminiferous tubules. A high association was found with unusual features, including bilaterality (six cases), multifocality (six cases), complex endocrine disorders, (three cases), and familial occurrence and cardiac myxoma (two cases). Eleven of the 12 cases had benign courses, but one was associated with metastases that caused death.
报告了10例具有独特特征的睾丸肿瘤，其特点为细胞大、嗜酸性细胞质丰富且有钙化，同时还纳入了文献中的2例类似病例。通过其结构和细胞学特征，以及在生精小管内的频繁生长，确定了这些肿瘤起源于支持细胞。发现这些肿瘤与一些异常特征高度相关，包括双侧性（6例）、多灶性（6例）、复杂的内分泌紊乱（3例）以及家族性发病和心脏黏液瘤（2例）。12例中有11例病程呈良性，但有1例发生转移并导致死亡。
