海分枝杆菌对八种抗菌药物的体外敏感性
In vitro susceptibility of Mycobacterium marinum to eight antimicrobial agents.
作者信息
Sanders W J, Wolinsky E
出版信息
Antimicrob Agents Chemother. 1980 Oct;18(4):529-31. doi: 10.1128/AAC.18.4.529.
Abstract
The in vitro susceptibilities of 16 Mycobacterium marinum strains to eight antimicrobial agents were determined by the agar dilution technique. The most active drugs were amikacin and kanamycin. Tetracycline, doxycycline, and minocycline were inhibitory, predominantly at concentrations slightly below the expected blood and tissue levels. Trimethoprim-sulfamethoxazole and erythromycin demonstrated activity only at concentrations greater than those usually attained in serum and tissues. Gentamicin was relatively inactive.
摘要
采用琼脂稀释法测定了16株海分枝杆菌对8种抗菌药物的体外敏感性。活性最强的药物是阿米卡星和卡那霉素。四环素、多西环素和米诺环素具有抑制作用，主要是在略低于预期血液和组织水平的浓度下。甲氧苄啶-磺胺甲恶唑和红霉素仅在高于血清和组织中通常达到的浓度时才显示出活性。庆大霉素相对无活性。
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