磷酸镁对柱晶白霉素产生的刺激作用及其与氮分解代谢调节的相关性。
Stimulation of leucomycin production by magnesium phosphate and its relevance to nitrogen catabolite regulation.
作者信息
Omura S, Tanaka Y, Kitao C, Tanaka H, Iwai Y
出版信息
Antimicrob Agents Chemother. 1980 Nov;18(5):691-5. doi: 10.1128/AAC.18.5.691.
Abstract
Addition of magnesium phosphate [Mg3(PO4)2 x 8H2O] to a complex medium or to an ammonium ion-containing, chemically defined medium stimulated leucomycin production by Streptomyces kitasatoensis. Ammonium ions in high concentrations inhibited leucomycin production, but their limitation by magnesium phosphate led to the high production of the antibiotic.
摘要
向复合培养基或含铵离子的化学成分确定的培养基中添加磷酸镁[Mg3(PO4)2·8H2O]可刺激北里链霉菌产生柱晶白霉素。高浓度的铵离子会抑制柱晶白霉素的产生，但通过磷酸镁限制铵离子可导致抗生素的高产。
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