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骨水泥中甲基丙烯酸甲酯经肺的排泄(作者译)

[The excretion of methylmethacrylate from bone cement through the lungs (author's transl)].

作者信息

Eggert A, Eckert W, Seidel H

出版信息

Arch Orthop Trauma Surg (1978). 1980;97(3):221-4. doi: 10.1007/BF00389730.

DOI:10.1007/BF00389730
PMID:7447672
Abstract

By using a continuous infra-red monitoring technique, it could be shown that in 42 patients undergoing TEP surgery methylmethacrylate is excreted through the lungs. The amount of monomer eliminated in the exhaled air is less following acetabulum implantation than following femoral shaft implantation. The concentration of monomer in the exhaled air is strongly influenced by measures such as femoral shaft drainage, washing the implantation site with icewater and lengthening the cement mixing time which reduce the transfer of the monomer. Pulmonary elimination of MMA-monomer takes 20 min and is very fast.

摘要

通过使用连续红外监测技术,可以证明,在42例行经皮内镜下腰椎间盘切除术(TEP)的患者中,甲基丙烯酸甲酯通过肺部排出。髋臼植入后呼出空气中消除的单体量比股骨干植入后少。呼出空气中单体的浓度受股骨干引流、用冰水冲洗植入部位以及延长骨水泥混合时间等措施的强烈影响,这些措施会减少单体的转移。甲基丙烯酸甲酯单体的肺部消除需要20分钟,而且非常迅速。

相似文献

1
[The excretion of methylmethacrylate from bone cement through the lungs (author's transl)].骨水泥中甲基丙烯酸甲酯经肺的排泄(作者译)
Arch Orthop Trauma Surg (1978). 1980;97(3):221-4. doi: 10.1007/BF00389730.
2
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Chirurg. 1974 May;45(5):236-42.
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Chirurg. 1977 May;48(5):316-8.
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[Comparative circulatory studies during implantation of total endoprostheses using methylmethacrylate and BDF cement].
Anasth Intensivther Notfallmed. 1983 Dec;18(6):291-5.
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Pre-packed vacuum bone cement mixing systems. A further step in reducing methylmethacrylate exposure in surgery.预包装真空骨水泥混合系统。减少手术中甲基丙烯酸甲酯暴露的又一举措。
Ann Occup Hyg. 2010 Nov;54(8):955-61. doi: 10.1093/annhyg/meq045. Epub 2010 Jun 30.
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Clin Orthop Relat Res. 1993 Feb(287):112-6.
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[Monomeric-delivery of harden bone cement-experimental determinations (author's transl)].[硬化骨水泥的单体递送——实验测定(作者译)]
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A device to improve the extrusion of bone cement into the bone of the acetabulum in the replacement of the hip joint.一种用于在髋关节置换术中改善骨水泥向髋臼骨内挤压的装置。
Biomed Eng. 1974 Nov;9(11):522-4.
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[Release and diffusion of methylmethacrylic monomers after the implantation of self curing bone cements. Study on laboratory specimens and animal experiments (author's transl)].[自固化骨水泥植入后甲基丙烯酸甲酯单体的释放与扩散。实验室标本及动物实验研究(作者译)]
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本文引用的文献

1
[Penetration of methylmethacrylate-monomer in blood circulation following hip joint prosthesis surgery in man].[人工髋关节置换术后甲基丙烯酸甲酯单体在人体血液循环中的渗透情况]
Chirurg. 1974 May;45(5):236-42.
2
[Influence of the bone-cement mixing time on hypotonic blood circulation reactions in hip-joint replacement surgery].[骨水泥搅拌时间对髋关节置换手术中低渗性血液循环反应的影响]
Chirurg. 1975 May;46(5):236-9.
3
Fate of methyl methacrylate in rats.大鼠体内甲基丙烯酸甲酯的代谢情况
Br J Cancer. 1977 Jul;36(1):114-9. doi: 10.1038/bjc.1977.161.
4
[Pharmacokinetics of methylmethacrylate monomer of bone cements: method for qualitative and quantitative monomer determination in respiratory air].[骨水泥甲基丙烯酸甲酯单体的药代动力学:呼吸空气中单体定性和定量测定方法]
Chirurg. 1977 May;48(5):316-8.
5
Some aspects of pulmonary excretion of methylmethacrylate monomer (MMM) in dogs.犬体内甲基丙烯酸甲酯单体(MMM)经肺排泄的某些方面。
J Surg Res. 1977 Jan;22(1):9-15. doi: 10.1016/0022-4804(77)90118-4.
6
Methylmethacrylate metabolism in man. The hydrolysis of methylmethacrylate to methacrylic acid during total hip replacement.
Clin Orthop Relat Res. 1979 Jun(141):90-5.