Barr C C, Glaser J S, Blankenship G
Arch Ophthalmol. 1980 Dec;98(12):2185-92. doi: 10.1001/archopht.1980.01020041037006.
Acute disc swelling was documented in 21 eyes of 12 patients with long-standing juvenile diabetes. All but one patient were in the second or third decade of life, with a 13-year average duration of diabetes. Seventeen eyes had initial acuity of 20/50 or better, including nine eyes with 20/25 or better; disc swelling was asymptomatic in six eyes. Simultaneous bilateral disc swelling occurred in seven patients. With no specific therapy, vision generally recovered to normal levels within a few weeks, but a few patients retained arcuate, nerve fiber bundle, field defects and optic atrophy. There was no positive correlation with the degree of diabetic retinopathy, and disc swelling did not seem to be a harbinger of progressive retinopathy or proliferation at the nerve head. Disc swelling in juvenile diabetics represents a distinct clinical entity that must be distinguished from other causes of acquired nerve head elevation, especially papilledema of increased intracranial pressure.
在12例患有长期青少年糖尿病的患者的21只眼中记录到急性视盘肿胀。除1例患者外，所有患者均处于第二或第三个十年，糖尿病平均病程为13年。17只眼的初始视力为20/50或更好，其中9只眼的视力为20/25或更好；6只眼的视盘肿胀无症状。7例患者出现双侧同时性视盘肿胀。在没有特殊治疗的情况下，视力通常在几周内恢复到正常水平，但少数患者保留了弓形、神经纤维束视野缺损和视神经萎缩。与糖尿病视网膜病变的程度没有正相关，视盘肿胀似乎不是进行性视网膜病变或视乳头增殖的先兆。青少年糖尿病患者的视盘肿胀代表一种独特的临床实体，必须与获得性视乳头抬高的其他原因，特别是颅内压升高引起的视乳头水肿相鉴别。
