Pavan P R, Aiello L M, Wafai M Z, Briones J C, Sebestyen J G, Bradbury M J
Arch Ophthalmol. 1980 Dec;98(12):2193-5. doi: 10.1001/archopht.1980.01020041045007.
The clinical and photographic records of patients with juvenile-onset diabetes and nonneurologic disc edema were reviewed to determine the natural history of the disease. Six female and two male patients, 14 to 40 years old, who had had diabetes for seven to 22 years had no visual complaints or mild blurring. All had 6/9 or better visual acuity and normal blood pressure. Visual fields were normal or showed an enlarged blind spot. The edematous discs had superficial, dilated, radially oriented, fluorescein-incontinent capillaries. Two patients had simultaneous neovascularization of the disc. Three received laser photocoagulation, and five received no therapy. In the seven followed up for six months or more, the edema resolved, resulting in 6/6 visual acuity. These findings suggest the edema resulted from a reversible vasculopathy that, due to few symptoms, may be more common than is presently appreciated.
对青少年起病型糖尿病合并非神经源性视盘水肿患者的临床及影像记录进行回顾，以确定该疾病的自然病程。6名女性和2名男性患者，年龄在14至40岁之间，患糖尿病7至22年，无视力主诉或仅有轻度视物模糊。所有患者视力均为6/9或更佳，血压正常。视野正常或显示盲点扩大。水肿视盘有表浅、扩张、呈放射状排列的荧光素渗漏毛细血管。2例患者视盘同时出现新生血管。3例接受了激光光凝治疗，5例未接受治疗。在随访6个月或更长时间的7例患者中，水肿消退，视力恢复至6/6。这些发现提示水肿是由可逆性血管病变引起的，由于症状较少，其实际发生率可能比目前所认识到的更高。
