Comparative efficacy of salbutamol by pressurized aerosol and wet nebulizer in acute asthma.
作者信息
Tarala R A, Madsen B W, Paterson J W
出版信息
Br J Clin Pharmacol. 1980 Oct;10(4):393-7. doi: 10.1111/j.1365-2125.1980.tb01776.x.
Abstract
1 Cumulative dose-response curves (FEV1) to pressurized aerosol salbutamol were established in 17 patients admitted to hospital with acute severe asthma. After the maximal pressurized aerosol effect had been achieved, a further dose (5 mg) of salbutamol was given by wet nebulizer and any further increment recorded. 2 Baseline FEV1 was 1.16 +/- 0.55 (mean +/- s.d.), an average of 36% of predicted, and the maximal aerosol induced change in FEV1 was 0.435 +/- 0.330 1 (t = 5.72, P < 0.01). There was an additional, small increment in FEV1 after nebulizer of 0.043 +/- 0.085 1 (t = 2.26, P < 0.05). 3 Detailed analysis of the data according to a theoretical dose-response relationship showed that the nebulizer-aerosol increment was unrelated to asthma severity.
摘要
相似文献
1
Comparative efficacy of salbutamol by pressurized aerosol and wet nebulizer in acute asthma.
Br J Clin Pharmacol. 1980 Oct;10(4):393-7. doi: 10.1111/j.1365-2125.1980.tb01776.x.
2
A comparison of albuterol administered by metered dose inhaler (and holding chamber) or wet nebulizer in acute asthma.
Chest. 1993 Sep;104(3):835-41. doi: 10.1378/chest.104.3.835.
3
A comparison of salbutamol given by pressure-packed aerosol or nebulization via IPPB in acute asthma.
Br J Dis Chest. 1978 Jul;72(3):222-4. doi: 10.1016/0007-0971(78)90045-1.
4
Effect of intravenous injection of salbutamol in asthma.
Br J Clin Pharmacol. 1975 Dec;2(6):495-501. doi: 10.1111/j.1365-2125.1975.tb00566.x.
5
Salbutamol inhalation in chronic asthma bronchiale: dose aerosol vs jet nebulizer.
Chest. 1981 Apr;79(4):416-9. doi: 10.1378/chest.79.4.416.
6
Comparison of salbutamol Rotahaler with conventional pressurized aerosol.
Clin Allergy. 1977 Nov;7(6):563-8. doi: 10.1111/j.1365-2222.1977.tb01486.x.
7
A comparison of responses to albuterol delivered by two aerosol devices.
Chest. 1986 Sep;90(3):392-5. doi: 10.1378/chest.90.3.392.
8
Randomized controlled trial of salbutamol aerosol therapy via metered dose inhaler-spacer vs. jet nebulizer in young children with wheezing.
Pediatr Pulmonol. 2005 May;39(5):466-72. doi: 10.1002/ppul.20204.
9
Bronchodilating effect and side effects of beta2- adrenoceptor stimulants by different modes of administration (tablets, metered aerosol, and combinations thereof). A study with salbutamol in asthmatics.
Am Rev Respir Dis. 1977 Nov;116(5):861-9. doi: 10.1164/arrd.1977.116.5.861.
10
Prevention of exercise-induced bronchospasm in pediatric asthma patients: a comparison of salmeterol powder with albuterol.
Ann Allergy Asthma Immunol. 1999 Feb;82(2):205-11. doi: 10.1016/S1081-1206(10)62598-7.
引用本文的文献
1
Holding chambers (spacers) versus nebulisers for beta-agonist treatment of acute asthma.
Cochrane Database Syst Rev. 2013 Sep 13;2013(9):CD000052. doi: 10.1002/14651858.CD000052.pub3.
2
3
Maximum or mean FEV1 for bronchodilator aerosol evaluation in acute asthmatics.
Br J Clin Pharmacol. 1981 Jun;11(6):631-3. doi: 10.1111/j.1365-2125.1981.tb01185.x.
4
Comparison of three techniques of inhalation on the airway response to terbutaline.
Thorax. 1983 Dec;38(12):908-13. doi: 10.1136/thx.38.12.908.
5
Combination bronchodilator therapy.
Drugs. 1982 Nov;24(5):414-39. doi: 10.2165/00003495-198224050-00004.
6
Nebulised fenoterol compared with metered aerosol.
Arch Dis Child. 1985 Mar;60(3):257-9. doi: 10.1136/adc.60.3.257.
本文引用的文献
1
COMPARATIVE EFFECTS OF ISOPROTERENOL AEROSOLS ON AIRWAY RESISTANCE IN OBSTRUCTIVE PULMONARY DISEASES.
Am J Med Sci. 1965 Mar;249:309-15. doi: 10.1097/00000441-196503000-00010.
2
PREDICTION VALUES FOR SCREENING TESTS OF PULMONARY FUNCTION.
Am Rev Respir Dis. 1965 Feb;91:252-61. doi: 10.1164/arrd.1965.91.2.252.
3
Investigation into use of drugs preceding death from asthma.
Br Med J. 1968 Feb 10;1(5588):339-43. doi: 10.1136/bmj.1.5588.339.
4
Normal standards for ventilatory function using an automated wedge spirometer.
Am Rev Respir Dis. 1972 Jul;106(1):38-46. doi: 10.1164/arrd.1972.106.1.38.
5
A comparison of three different techniques for giving nebulized albuterol to asthmatic patients.
Am Rev Respir Dis. 1974 Feb;109(2):293-5. doi: 10.1164/arrd.1974.109.2.293.
6
Rise and fall of asthma mortality in England and Wales in relation to use of pressurised aerosols.
Lancet. 1969 Aug 9;2(7615):279-85. doi: 10.1016/s0140-6736(69)90051-8.
7
Comparison of two methods of administering bronchodilator aerosol to asthmatic patients.
Br Med J. 1975 Apr 19;2(5963):119-20. doi: 10.1136/bmj.2.5963.119.
8
Aerosol salbutamol administration by IPPB: lowest effective dose.
Thorax. 1978 Dec;33(6):689-93. doi: 10.1136/thx.33.6.689.
9
A comparison of salbutamol given by pressure-packed aerosol or nebulization via IPPB in acute asthma.
Br J Dis Chest. 1978 Jul;72(3):222-4. doi: 10.1016/0007-0971(78)90045-1.
Zotero 插件