Hetzel M R, Clark T J
Clin Allergy. 1977 Nov;7(6):563-8. doi: 10.1111/j.1365-2222.1977.tb01486.x.
Salbutamol in a powder aerosol from the Rotahaler insufflator was compared, with equal doses of the conventional pressurized aerosol by dose-response curves and in a 1 month open trial, in the treatment of asthma patients with good inhalation technique. Results were not significantly different in either study. A further group of asthma patients, who were known to be incapable of using pressurized aerosols effectively, were shown to benefit from treatment with the Rotahaler. This device should increase the value of the sympathomimetic drugs to the minority of asthma patients who cannot use conventional aerosols correctly.
将喘乐宁通过旋转吸入器制成粉末气雾剂，与等剂量的传统压力定量气雾剂进行比较，通过剂量反应曲线以及在一项为期1个月的开放试验中，用于治疗具有良好吸入技术的哮喘患者。两项研究结果均无显著差异。另一组已知无法有效使用压力定量气雾剂的哮喘患者，经证明使用旋转吸入器治疗有益。对于少数无法正确使用传统气雾剂的哮喘患者，该装置应能提高拟交感神经药物的价值。
