雾化吸入的非诺特罗与定量气雾剂的比较。

Nebulised fenoterol compared with metered aerosol.

作者信息

Melville C, Phelan P D, Landau L I

出版信息

Arch Dis Child. 1985 Mar;60(3):257-9. doi: 10.1136/adc.60.3.257.

DOI:10.1136/adc.60.3.257

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1777195/

Abstract

The effect of nebulised fenoterol was compared with that of a similar dose administered by metered aerosol in 14 children, aged 7 to 17 years with moderately severe asthma. The initial response to fenoterol delivered by metered aerosol or nebuliser was the same, but a second dose by nebuliser after a dose by metered aerosol produced maximum potential bronchodilatation which was not seen when a second dose by metered aerosol was given after that by nebuliser. Administration of a bronchodilator by nebuliser does seem advantageous in the treatment of some children.

摘要

对14名年龄在7至17岁、患有中度严重哮喘的儿童，比较了雾化吸入非诺特罗与通过定量气雾剂给予相似剂量非诺特罗的效果。通过定量气雾剂或雾化器给予非诺特罗的初始反应相同，但在定量气雾剂给药后再进行一次雾化器给药可产生最大潜在支气管扩张作用，而在雾化器给药后再给予定量气雾剂第二次剂量时则未观察到这种情况。对于一些儿童的治疗，通过雾化器给予支气管扩张剂似乎确实具有优势。

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本文引用的文献

1

Comparative efficacy of salbutamol by pressurized aerosol and wet nebulizer in acute asthma.沙丁胺醇通过压力定量气雾剂和湿式雾化器治疗急性哮喘的疗效比较

Br J Clin Pharmacol. 1980 Oct;10(4):393-7. doi: 10.1111/j.1365-2125.1980.tb01776.x.

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Dose-response characteristics of nebulized fenoterol in asthmatic children.

J Pediatr. 1983 Jul;103(1):121-6. doi: 10.1016/s0022-3476(83)80797-5.

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Clinical assessment of bronchodilator drugs delivered by aerosol.气雾剂递送的支气管扩张剂药物的临床评估

Thorax. 1973 Mar;28(2):124-8. doi: 10.1136/thx.28.2.124.

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Comparison of two methods of administering bronchodilator aerosol to asthmatic patients.两种向哮喘患者施用支气管扩张气雾剂方法的比较。

Br Med J. 1975 Apr 19;2(5963):119-20. doi: 10.1136/bmj.2.5963.119.

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Site of beta-adrenergic receptors in the respiratory tract: use of fenoterol administered by two methods.呼吸道中β-肾上腺素能受体的部位：两种给药方法使用非诺特罗的情况。

Chest. 1978 Sep;74(3):256-60. doi: 10.1378/chest.74.3.256.

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