Hoag G N, Franks C R, Smith C, DeCoteau W E
Clin Biochem. 1980 Aug;13(4):149-50. doi: 10.1016/s0009-9120(80)91027-9.
The CK isoenzyme composition of leiomyoma tissue is predominantly CK-BB and similar to adjacent myometrium tissue, while the leiomyosarcoma revealed a lesser quantity of CK-BB, but a greater quantity of CK-MM. The reasons for the discrepancy between the two types of neoplasms is not clear, but may reflect the changes which occur when smooth muscle becomes malignant.
平滑肌瘤组织的肌酸激酶同工酶组成主要为脑型肌酸激酶(CK-BB),与相邻的子宫肌层组织相似,而平滑肌肉瘤显示脑型肌酸激酶(CK-BB)的量较少,但肌型肌酸激酶(CK-MM)的量较多。这两种肿瘤之间差异的原因尚不清楚,但可能反映了平滑肌发生恶变时所发生的变化。