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[麻醉性角膜炎(作者译)]

[Anesthetic keratitis (author's transl)].

作者信息

Pau H

出版信息

Klin Monbl Augenheilkd. 1980 Jun;176(6):885-92. doi: 10.1055/s-2008-1057577.

DOI:10.1055/s-2008-1057577
PMID:7453012
Abstract

Report of six patients with corneal lesions due to abuse of local anesthetics. Depending on the duration and frequency of application of local anesthetics and individual disposition, the following lesions occur: superficial punctate keratitis, corneal erosions, edema of epithelium and stroma, stromal infiltrates, stromal defects, iritis, cataract, secondary glaucoma. During the prolonged period of healing following a stromal affection, bullae of the epithelium and erosions occur at these sites repeatedly in some cases; vascularization and leukoma may also occur. The most important local anesthetics currently in use are mentioned. Local anesthetics for the eye should only be administered by the physician.

摘要

6例因滥用局部麻醉剂导致角膜病变的病例报告。根据局部麻醉剂的使用时间、频率及个体差异,会出现以下病变:浅层点状角膜炎、角膜糜烂、上皮及基质水肿、基质浸润、基质缺损、虹膜炎、白内障、继发性青光眼。在基质病变后的较长愈合期,某些病例中这些部位会反复出现上皮大疱和糜烂;还可能出现血管化和角膜白斑。文中提及了目前使用的最重要的局部麻醉剂。眼部局部麻醉剂应由医生使用。

相似文献

1
[Anesthetic keratitis (author's transl)].[麻醉性角膜炎(作者译)]
Klin Monbl Augenheilkd. 1980 Jun;176(6):885-92. doi: 10.1055/s-2008-1057577.
2
Clinical findings in patients with topical anaesthetic abuse keratitis: a report of five cases.表面麻醉剂滥用性角膜炎患者的临床发现:5例报告
Klin Monbl Augenheilkd. 2007 Apr;224(4):303-8. doi: 10.1055/s-2007-962933.
3
Topical anesthetic abuse ring keratitis: report of four cases.局部麻醉药滥用性角膜炎:4例报告
Cornea. 1997 Jul;16(4):424-9.
4
[A clinico-pathological case report of necrotizing ulcerating keratopathy due to topical anaesthetic abuse].[一例因滥用局部麻醉剂导致坏死性溃疡性角膜病变的临床病理病例报告]
Ophthalmologe. 2002 Nov;99(11):872-5. doi: 10.1007/s00347-002-0623-z.
5
Toxicity of topical ophthalmic anesthetics.局部眼科麻醉剂的毒性。
Expert Opin Drug Metab Toxicol. 2013 Aug;9(8):983-8. doi: 10.1517/17425255.2013.794219. Epub 2013 Apr 25.
6
Keratitis from misuse of corneal anesthetics.角膜麻醉剂滥用所致角膜炎
N Engl J Med. 1968 Aug 22;279(8):396-9. doi: 10.1056/NEJM196808222790802.
7
[The influence of local anesthetics on corneal epithelium. A scanning electron microscopic study (author's transl)].[局部麻醉药对角膜上皮的影响。扫描电子显微镜研究(作者译)]
Klin Monbl Augenheilkd. 1978 Sep;173(3):347-54.
8
Toxic keratopathy due to abuse of topical anesthetic drugs.滥用局部麻醉药物所致的中毒性角膜病。
Cutan Ocul Toxicol. 2010 Jun;29(2):105-9. doi: 10.3109/15569521003631752.
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[Keratitis due to prolonged use of anesthetic eyedrops; apropos of 3 new cases].[长期使用麻醉眼药水导致的角膜炎;关于3例新病例]
Bull Soc Ophtalmol Fr. 1975 Jan;75(1):31-5.
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Topical anesthetic abuse keratitis secondary to floppy eyelid syndrome.因眼睑松弛综合征导致的局部麻醉剂滥用性角膜炎。
Cornea. 2011 Jan;30(1):105-6. doi: 10.1097/ICO.0b013e3181e458af.

引用本文的文献

1
Toxic side effects of local anaesthetics on the human cornea.局部麻醉药对人角膜的毒性副作用。
Br J Ophthalmol. 1994 May;78(5):386-9. doi: 10.1136/bjo.78.5.386.