Costeloe K, Rolfe P
Pediatr Res. 1980 Sep;14(9):1053-60. doi: 10.1203/00006450-198009000-00007.
This study aims to define a method for acquiring limb flood flow data from newborn babies on a continuous basis which would be suitable for automatic processing. Pulsatile electrical impedance and strain gauge signals were analyzed in 3 different ways. The results were compared with estimates of flow derived from venous occlusion plethysmography with a mercury-in-rubber strain gauge. Measurements were made from 33 babies. The impedance technique was easier to perform than the strain gauge technique. The reproducibility of the various estimates of flow is shown in Table 3. The beat-to-beat reproducibility of simultaneous pulsatile mesurements and of repeated measurements on different subjects was greater from the impedance recordings than from the strain gauge recordings. The results of linear regression analyses between the different flow estimates are shown in Table 4. The best correlation with flow measured using venous occlusion plethysmography was with flow calculated from the impedance pulse height, F(Zmax) (r = 0.76; n = 30; P < 0.001). The regression line between these 2 variables was not statistically significantly different from the line of identity, (P < 0.98), and the intercept is close to zero. The measurement of the impedance pulse height, delta Zmax, and the subsequent calculation of F(Zmax) could be automated and provide continuous beat-to-beat blood flow estimations.
本研究旨在确定一种能够持续获取新生儿肢体血流数据的方法，该方法应适用于自动处理。对搏动性电阻抗和应变仪信号进行了3种不同方式的分析。将结果与采用橡皮内置汞应变仪的静脉阻塞体积描记法得出的血流估计值进行比较。对33名婴儿进行了测量。电阻抗技术比应变仪技术更易于操作。表3显示了各种血流估计值的可重复性。与应变仪记录相比，电阻抗记录在不同受试者上进行的同步搏动测量和重复测量的逐搏可重复性更高。表4显示了不同血流估计值之间的线性回归分析结果。与采用静脉阻塞体积描记法测量的血流相关性最好的是根据电阻抗脉冲高度F(Zmax)计算得出的血流(r = 0.76；n = 30；P < 0.001)。这两个变量之间的回归线与恒等线在统计学上无显著差异(P < 0.98)，且截距接近零。电阻抗脉冲高度delta Zmax的测量以及随后F(Zmax)的计算可以实现自动化，并提供连续的逐搏血流估计值。
