Powers W F, Swyer P R
Pediatrics. 1975 Aug;56(2):203-7.
We applied continuous positive transpulmonary pressure (CPTP) by face mask to 22 spontaneously breathing infants who were free from cardiorespiratory disease, and measured resultant changes in peak esophageal pressure (Pes) and peripheral perfusion (Q1). We measured Pes by balloon and transducer, and Q1 by venous occlusion plethysmography with a mercury-in-rubber strain gauge. Application of 7.6 cm H2O CPTP led to a 13% decrease in Q1 (paired t-test=2.39; P less than .02). Thirty-two percent of the applied CPTP was detected as a change in Pes. The biological significance of a 13% decrease in peripheral perfusion is probably minimal.
我们通过面罩对22名无心肺疾病的自主呼吸婴儿施加持续的经肺正压（CPTP），并测量由此引起的食管峰值压力（Pes）和外周灌注（Q1）的变化。我们通过球囊和传感器测量Pes，通过带有橡胶汞应变计的静脉阻断体积描记法测量Q1。施加7.6 cm H2O的CPTP导致Q1降低13%（配对t检验=2.39；P<0.02）。施加的CPTP中有32%被检测为Pes的变化。外周灌注降低13%的生物学意义可能很小。
