Couvreur J, Tournier G, Grimfeld A, Le Moing G
Nouv Presse Med. 1980 Nov 15;9(43):3245-8.
The early onset of the disease (between the 13th and 15th days of life) and its long duration in 2 out of 3 cases, the absence of infectious symptoms and the efficacy of erythromycin treatment were characteristic features. The diagnosis was confirmed by positive (greater than 1/32th) serological tests in both infants and parents. Chlamydia trachomatis lung infection should be suspected in infants presenting, during the first weeks of life, with cough and dyspnoea unaccompanied by fever, radiological evidence of interstitial pneumonia, blood eosinophilia and raised immunoglobulin levels. The disease results from intranatal contamination and might represent, in France as in the U.S.A., an important percentage of respiratory infections occurring during the early months of life.
该病发病早(出生后第13至15天之间),3例中有2例病程长,无感染症状以及红霉素治疗有效是其特征。婴儿及其父母血清学检测呈阳性(大于1/32)确诊该病。对于出生后最初几周出现咳嗽和呼吸困难但不伴有发热、间质性肺炎的影像学证据、血液嗜酸性粒细胞增多和免疫球蛋白水平升高的婴儿,应怀疑沙眼衣原体肺部感染。该病由产时感染所致,在法国和美国,可能占生命最初几个月发生的呼吸道感染的很大比例。