Butler A R, Passalaqua A M, Berenstein A, Kricheff I I
Neuroradiology. 1978;16:491-4. doi: 10.1007/BF00395343.
The preoperative contrast-enhanced CT scan and the radionuclide brain scan of 70 patients with surgically verified supratentorial astrocytomas were evaluated and compared. The results indicate parallel mechanisms of action of contrast enhancement and radionuclide uptake. These diagnostic modalities apparently mirror the integrity of the blood-brain barrier (BBB) and therefore are useful in assessing the degree of malignancy of supratentorial gliomas. However, lesions with an intact BBB will be missed with RN imaging. These lesions and/or the associated mass effect will be detected with contrast-enhanced computed tomography. Our findings firmly establish contrast-enhanced CT as the primary investigate tool in the suspected brain tumor.
对70例经手术证实的幕上星形细胞瘤患者的术前增强CT扫描和放射性核素脑扫描进行了评估和比较。结果表明，对比增强和放射性核素摄取具有平行的作用机制。这些诊断方式显然反映了血脑屏障（BBB）的完整性，因此有助于评估幕上胶质瘤的恶性程度。然而，放射性核素成像会漏诊血脑屏障完整的病变。这些病变和/或相关的占位效应可通过增强CT检测到。我们的研究结果明确将增强CT确立为疑似脑肿瘤的主要检查工具。
