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通过核磁共振进行内部结构映射。

Internal structural mapping by nuclear magnetic resonance.

作者信息

Hinshaw W S, Andrew E R, Bottomley P A, Holland G N, Moore W S, Worthington B S

出版信息

Neuroradiology. 1978;16:607-9. doi: 10.1007/BF00395378.

DOI:10.1007/BF00395378
PMID:745773
Abstract

Nuclear magnetic resonance (NMR) is a well-established tool for studying the properties of materials at the molecular level. The technique has recently been applied to the internal morphological analysis of biological material by producing a series of thin cross-sectional images derived from the distribution of mobile protons. There are grounds for believing that NMR will be more than a mere alternative to computer tomography, for it may prove possible to achieve both a useful degree of tissue characterization through analysing components of the complex NMR signal and also an approach to the measurement of blood flow in vivo.

摘要

核磁共振(NMR)是一种成熟的工具,用于在分子水平上研究材料的特性。最近,该技术已应用于生物材料的内部形态分析,通过生成一系列源自移动质子分布的薄横截面图像来实现。有理由相信,NMR将不仅仅是计算机断层扫描的一种替代方法,因为通过分析复杂NMR信号的成分,有可能实现有用程度的组织特征描述,并且还可能找到一种在体内测量血流的方法。

相似文献

1
Internal structural mapping by nuclear magnetic resonance.通过核磁共振进行内部结构映射。
Neuroradiology. 1978;16:607-9. doi: 10.1007/BF00395378.
2
Radiographic thin-section image of the human wrist by nuclear magnetic resonance.
Nature. 1977;270(5639):722-3. doi: 10.1038/270722a0.
3
Translational Metabolomics of Head Injury: Exploring Dysfunctional Cerebral Metabolism with Ex Vivo NMR Spectroscopy-Based Metabolite Quantification头部损伤的转化代谢组学:基于体外核磁共振波谱的代谢物定量分析探索脑代谢功能障碍
4
Observation of exchangeable protons by high-performance liquid chromatography-nuclear magnetic resonance spectroscopy and high-performance liquid chromatography-electrospray ionization mass spectrometry: a useful tool for the hyphenated analysis of natural products.通过高效液相色谱-核磁共振光谱法和高效液相色谱-电喷雾电离质谱法观察可交换质子:用于天然产物联用分析的有用工具。
J Chromatogr A. 2000 Dec 29;904(2):243-9. doi: 10.1016/s0021-9673(00)00926-2.
5
[NMR-intrascopy - new method of biophysical investigation].[核磁共振内镜检查——生物物理研究的新方法]
Biofizika. 1982 Jan-Feb;27(1):170-8.
6
Quantification of water content in biological tissues by proton nuclear magnetic resonance.通过质子核磁共振对生物组织中的含水量进行定量分析。
Tokai J Exp Clin Med. 1991 Oct;16(3-4):175-81.
7
[Detection of cancer by nuclear magnetic resonance imaging].[通过核磁共振成像检测癌症]
Gan No Rinsho. 1983 Aug;29(10):1186-90.
8
Nuclear magnetic resonance (NMR): I. Imaging biochemical change.核磁共振(NMR):I. 成像生化变化。
Br J Psychiatry. 1985 Jan;146:26-31. doi: 10.1192/bjp.146.1.26.
9
An in vivo study of the fore-arm and hand by thin section NMR imaging.通过薄层核磁共振成像对前臂和手部进行的一项体内研究。
Br J Radiol. 1979 Jan;52(613):36-43. doi: 10.1259/0007-1285-52-613-36.
10
In vivo tissue analysis by NMR spectroscopy.通过核磁共振波谱法进行体内组织分析。
Diagn Imaging Clin Med. 1986;55(1-2):9-19.

本文引用的文献

1
Relationship between hydration and proton nuclear magnetic resonance relaxation times in tissues of tumor-bearing and non-tumor-bearing mice: implications for cancer detection.荷瘤小鼠和非荷瘤小鼠组织中水分与质子核磁共振弛豫时间的关系:对癌症检测的意义
J Natl Cancer Inst. 1974 Jun;52(6):1849-53. doi: 10.1093/jnci/52.6.1849.
2
Image formation by induced local interactions. Examples employing nuclear magnetic resonance. 1973.通过诱导局部相互作用形成图像。核磁共振示例。1973年。
Clin Orthop Relat Res. 1989 Jul(244):3-6.
3
NMR images by the multiple sensitive point method: application to larger biological systems.
Phys Med Biol. 1977 Sep;22(5):971-4. doi: 10.1088/0031-9155/22/5/016.
4
Medical imaging by NMR.核磁共振医学成像
Br J Radiol. 1977 Mar;50(591):188-94. doi: 10.1259/0007-1285-50-591-188.
5
Display of cross sectional anatomy by nuclear magnetic resonance imaging.通过核磁共振成像展示横断面解剖结构。
Br J Radiol. 1978 Apr;51(604):273-80. doi: 10.1259/0007-1285-51-604-273.
6
Radiographic thin-section image of the human wrist by nuclear magnetic resonance.
Nature. 1977;270(5639):722-3. doi: 10.1038/270722a0.
7
Nuclear magnetic resonance studies of cancer. VI. Relationship among spin-lattice relaxation times, growth rate, and water content of Morris hepatomas.癌症的核磁共振研究。VI. 莫里斯肝癌的自旋晶格弛豫时间、生长速率与含水量之间的关系。
J Natl Cancer Inst. 1975 Jun;54(6):1469-72. doi: 10.1093/jnci/54.6.1469.