Hollis D P, Saryan L A, Eggleston J C, Morris H P
J Natl Cancer Inst. 1975 Jun;54(6):1469-72. doi: 10.1093/jnci/54.6.1469.
Relaxation time(s) (T1), growth rates, and the water content of six Morris hepatomas, several murine tumors, and a selection of normal tissues indicated that malignant tumors did not always exhibit longer T1 values than any normal tissue, as previously suspected. This overlap raised the possibility of confusion between normal and malignant tissues studied by this method. Tissue T1 values depended primarily on the hydration of the tissue and correlated well with water content determinations. A rough correlation of T1 and water content with tumor growth rate was also observed.
六种莫里斯肝癌、几种鼠类肿瘤以及一些正常组织的弛豫时间（T1）、生长速率和含水量表明，恶性肿瘤并不总是如之前所怀疑的那样，其T1值比任何正常组织都长。这种重叠增加了用该方法研究正常组织和恶性组织时产生混淆的可能性。组织T1值主要取决于组织的水合作用，并且与含水量测定结果相关性良好。还观察到T1和含水量与肿瘤生长速率之间存在粗略的相关性。
