Escoula L, Larrieu G
Ann Rech Vet. 1980;11(2):119-22.
The growth of Byssochlamys nivea and P. granulatum was reduced by ochratoxin A (1 ppm, 10 ppm), whereas Aspergillus ochraceus growth and toxinogenesis were not affected by 1 and 10 ppm of patulin. When Penicillium granulatum and Asperigillus ochraceus were placed in the same medium the former grew and produced its toxin and ochratoxin production by the latter was weakened. Since patulin and ochratoxin can be found in the same substrate; the toxinogenic significance of in vitro strains is questionned.
赭曲霉毒素A(1 ppm、10 ppm)可抑制雪白丝衣霉和粒状青霉的生长,而展青霉素1 ppm和10 ppm对棕曲霉的生长及毒素生成没有影响。当将粒状青霉和棕曲霉置于同一培养基中时,前者生长并产生毒素,而后者的赭曲霉毒素生成则被削弱。由于展青霉素和赭曲霉毒素可存在于同一基质中,因此体外菌株产生毒素的意义受到质疑。