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绿头鸭和日本鹌鹑大脑中中催产素和加压催产素系统的拓扑结构:免疫细胞化学鉴定

The topography of mesotocin and vasotocin systems in the brain of the domestic mallard and Japanese quail: immunocytochemical identification.

作者信息

Bons N

出版信息

Cell Tissue Res. 1980;213(1):37-51. doi: 10.1007/BF00236919.

DOI:10.1007/BF00236919
PMID:7459995
Abstract

The neurosecretory systems producing mesotocin (MT) and vasotocin (VT) (the avian homologues of oxytocin and vasopressin, respectively) were characterized in the brains of the domestic mallard and Japanese quail by means of indirect immunofluorescence techniques using specific antisera. In the anterior preoptic region, including the organum vasculosum of the lamina terminalis, and at different levels of the supraoptic and paraventricular nuclei, separate mesotocin- and vasotocin-producing neurons were identified. Mesotocinergic and vasotocinergic neurons were also located in the tuberomammillary area, among the ectomammillary tract fibers. The supraoptico-neurohypophysial tract, formed by vasotocin- and mesotocin-containing axons, enters the internal zone of the median eminence and ends in the posterior lobe of the pituitary. The external zone of the rostral median eminence appears to contain vasotocin and mesotocin fibers, which terminate in close contact with the capillaries of the hypophysial portal system.

摘要

利用特异性抗血清,通过间接免疫荧光技术,在家鸭和日本鹌鹑的大脑中对产生中催产素(MT)和血管催产素(VT)(分别为催产素和加压素的鸟类同源物)的神经分泌系统进行了表征。在包括终板血管器在内的视前区前部以及视上核和室旁核的不同水平,鉴定出了分别产生中催产素和血管催产素的神经元。中催产素能和血管催产素能神经元也位于乳头体区,在外乳头体束纤维之间。由含血管催产素和中催产素的轴突形成的视上神经垂体束进入正中隆起的内侧区,并终止于垂体后叶。吻侧正中隆起的外侧区似乎含有血管催产素和中催产素纤维,它们终止于与垂体门脉系统毛细血管紧密接触的部位。

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