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[对1500名加蓬人进行血红蛋白电泳镰状细胞贫血症系统研究的结果]

[Results of a systematic study of drepanocytosis in 1,500 Gabonese using hemoglobin electrophoresis].

作者信息

Richard-Lenoble D, Toublanc J E, Zinsou R D, Kombila M, Carme B

出版信息

Bull Soc Pathol Exot Filiales. 1980 Mar-Apr;73(2):200-6.

PMID:7460122
Abstract

Hemoglobin electrophoresis realised as a routine screening test on 1 500 gabonese individuals revealed the existence of a sickle cell abnormality n 24.40% cases (22.27% were AS heterozygotous and 2.1% were SS homozygotous). Bapounov and Fang ethnies appeared to be the most involved. The importance of such disturbance (I gabonese individual out of 4 is concerned) could justify the creation of Prenatal Counseling Centers mainly dealing with this genetic problem.

摘要

对1500名加蓬人进行的血红蛋白电泳作为一项常规筛查测试,结果显示24.40%的病例存在镰状细胞异常(22.27%为AS杂合子,2.1%为SS纯合子)。巴普诺夫族和方族似乎受影响最大。这种疾病的严重性(每4名加蓬人中有1人受影响)足以说明有必要设立主要处理这一遗传问题的产前咨询中心。

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