Wistar大鼠脾细胞的自然杀伤活性：同源血清的阻断作用。
Natural killer activity of Wistar rat spleen cells: blocking effect of homologous sera.
作者信息
Lavrovsky V A, Viksler V K
出版信息
Immunology. 1980 Nov;41(3):541-5.
The natural killer (NK) activity of lymphocytes from Wistar rats against mouse target cells wa studied using the 24 h microplate assay. The cytotoxic activity of NK cells was blocked in the presence of sera from adult rats and man, but not in the presence of sera from adult rats and man, but not in the presence of sera from cattle, rabbits, mice or newborn rats. The blocking serum factor was non-dialysable and inactivated by trypsin. In addition, data were obtained indicating that several continuous cell lines of mice differ significantly in sensitivity to Wistar rat spleen cells.
使用24小时微孔板分析法研究了Wistar大鼠淋巴细胞对小鼠靶细胞的自然杀伤（NK）活性。NK细胞的细胞毒性活性在成年大鼠和人的血清存在下被阻断，但在牛、兔、小鼠或新生大鼠的血清存在下未被阻断。阻断血清因子不可透析且可被胰蛋白酶灭活。此外，获得的数据表明，小鼠的几种连续细胞系对Wistar大鼠脾细胞的敏感性存在显著差异。
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