淋巴细胞通过抗原刺激淋巴结的迁移。II. 前列腺素E2作为细胞休止介质的作用。
Lymphocyte traffic through antigen-stimulated lymph nodes. II. Role of Prostaglandin E2 as a mediator of cell shutdown.
作者信息
Hopkins J, McConnell I, Pearson J D
出版信息
Immunology. 1981 Feb;42(2):225-31.
Abstract
Prostaglandin E2 (PGE2) can mediate changes in lymphocyte traffic through lymph nodes. By measuring PGE2 levels in efferent lymph from cannulated sheep lymph nodes it was shown that increased synthesis of PGE2 always correlated with cell shutdown; infusion of PGE2 alone induced cell shutdown and inhibition of PGE2 synthesis by the node abolished cell shutdown induced by antigen.
摘要
前列腺素E2（PGE2）可介导淋巴细胞通过淋巴结的转运变化。通过测量来自插管羊淋巴结的输出淋巴液中的PGE2水平发现，PGE2合成增加总是与细胞停滞相关；单独输注PGE2可诱导细胞停滞，而淋巴结中PGE2合成的抑制则消除了抗原诱导的细胞停滞。
相似文献
1
2
3
4
Lymphocyte traffic through lymph nodes during cell shutdown.细胞静止期淋巴细胞通过淋巴结的运输
Ciba Found Symp. 1980;71:167-95. doi: 10.1002/9780470720547.ch10.
5
Antigen-induced non-specific suppressor factor in sheep efferent lymph is prostaglandin E2.绵羊传出淋巴中抗原诱导的非特异性抑制因子是前列腺素E2。
Immunology. 1981 May;43(1):205-12.
6
Relationships between changes in blood flow and lymphocyte migration induced by antigen.抗原诱导的血流变化与淋巴细胞迁移之间的关系。
Monogr Allergy. 1980;16:112-25.
7
The modulation by prostaglandins of increases in lymphocyte traffic induced by bradykinin.前列腺素对缓激肽诱导的淋巴细胞流量增加的调节作用。
Immunology. 1984 Mar;51(3):455-60.
8
Prostaglandin E2-induced inhibition of the in vitro immune response by SRBC-stimulated human lymphocytes.
Immunopharmacol Immunotoxicol. 1991;13(1-2):169-81. doi: 10.3109/08923979109019698.
9
10
Specific selection of antigen-reactive lymphocytes into antigenically stimulated lymph nodes in sheep.绵羊体内抗原反应性淋巴细胞向抗原刺激淋巴结的特异性募集。
J Exp Med. 1981 Mar 1;153(3):706-19. doi: 10.1084/jem.153.3.706.
引用本文的文献
1
Prolonged immune alteration following resolution of acute inflammation in humans.人类急性炎症消退后免疫改变的持续时间。
PLoS One. 2017 Oct 26;12(10):e0186964. doi: 10.1371/journal.pone.0186964. eCollection 2017.
2
Resolution of inflammation: a new therapeutic frontier.炎症消退：一个新的治疗前沿。
Nat Rev Drug Discov. 2016 Aug;15(8):551-67. doi: 10.1038/nrd.2016.39. Epub 2016 Mar 29.
3
Hypertrophy of infected Peyer's patches arises from global, interferon-receptor, and CD69-independent shutdown of lymphocyte egress.受感染派尔集合淋巴结的增生是由于淋巴细胞迁出的全局性、干扰素受体和 CD69 非依赖性关闭引起的。
Mucosal Immunol. 2014 Jul;7(4):892-904. doi: 10.1038/mi.2013.105. Epub 2013 Dec 18.
4
Neutrophils control the magnitude and spread of the immune response in a thromboxane A2-mediated process.中性粒细胞通过血栓素 A2 介导的过程控制免疫反应的幅度和范围。
J Exp Med. 2013 Feb 11;210(2):375-87. doi: 10.1084/jem.20122183. Epub 2013 Jan 21.
5
Fatty acids, the immune response, and autoimmunity: a question of n-6 essentiality and the balance between n-6 and n-3.脂肪酸、免疫反应与自身免疫：n-6 必需性以及 n-6 与 n-3 平衡的问题
Lipids. 2003 Apr;38(4):323-41. doi: 10.1007/s11745-003-1067-z.
6
Antigen-induced non-specific suppressor factor in sheep efferent lymph is prostaglandin E2.绵羊传出淋巴中抗原诱导的非特异性抑制因子是前列腺素E2。
Immunology. 1981 May;43(1):205-12.
7
8
Cyclosporin-A inhibits accumulation of lymphocytes within lymph nodes.环孢素A抑制淋巴细胞在淋巴结内的聚集。
Immunology. 1982 Oct;47(2):345-9.
9
10
Regulation of the immune response by prostaglandins.前列腺素对免疫反应的调节
J Clin Immunol. 1983 Oct;3(4):295-315. doi: 10.1007/BF00915791.
本文引用的文献
1
The output of cells in lymph from the popliteal node of sheep.绵羊腘淋巴结中淋巴细胞的输出
Q J Exp Physiol Cogn Med Sci. 1962 Oct;47:360-9. doi: 10.1113/expphysiol.1962.sp001620.
2
A quantitative immunochemical measure of the primary interaction between I BSA and antibody.一种对牛血清白蛋白（BSA）与抗体之间主要相互作用的定量免疫化学测定方法。
J Infect Dis. 1958 Nov-Dec;103(3):239-62. doi: 10.1093/infdis/103.3.239.
3
The distribution of prostaglandins in afferent and efferent lymph from inflammatory sites.前列腺素在来自炎症部位的输入淋巴管和输出淋巴管中的分布。
Am J Pathol. 1980 Jun;99(3):695-714.
4
Microcirculation of organized lymphoid tissues.有组织淋巴组织的微循环。
Monogr Allergy. 1980;16:126-42.
5
6
Lymphocyte traffic through lymph nodes during cell shutdown.细胞静止期淋巴细胞通过淋巴结的运输
Ciba Found Symp. 1980;71:167-95. doi: 10.1002/9780470720547.ch10.
7
8
The immediate effect of antigens on the cell output of a lymph node.抗原对淋巴结细胞输出量的即时影响。
Br J Exp Pathol. 1965 Aug;46(4):450-4.
9
The response of the popliteal lymph node of the sheep to swine influenza virus.绵羊腘淋巴结对猪流感病毒的反应。
Aust J Exp Biol Med Sci. 1970 Feb;48(1):33-46. doi: 10.1038/icb.1970.4.
10
Blood microcirculation in the lymph node during the primary immune response.初次免疫反应期间淋巴结内的血液微循环。
J Exp Med. 1972 Oct 1;136(4):697-714. doi: 10.1084/jem.136.4.697.
Zotero 插件